M
Marc Porzner
Researcher at University of Erlangen-Nuremberg
Publications - 3
Citations - 1129
Marc Porzner is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Gene & Internal medicine. The author has an hindex of 2, co-authored 2 publications receiving 1078 citations.
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Journal ArticleDOI
Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
Thomas Brabletz,Andreas Jung,Simone Reu,Marc Porzner,Falk Hlubek,Leoni A. Kunz-Schughart,Ruth Knuechel,Thomas Kirchner +7 more
TL;DR: It is postulate that an important driving force for progression of well-differentiated colorectal carcinomas is the specific environment, initiating two transient phenotypic transition processes by modulating intracellular β-catenin distribution in tumor cells.
Journal ArticleDOI
Alterations in the tissue inhibitor of metalloproteinase-3 (TIMP-3) are found frequently in human colorectal tumours displaying either microsatellite stability (MSS) or instability (MSI).
Wolfgang M. Brueckl,Jens Grombach,Axel Wein,Stefan Ruckert,Marc Porzner,Wolfgang Dietmaier,Petra Rümmele,Roland S. Croner,Frank Boxberger,Thomas Kirchner,Werner Hohenberger,Eckhart G. Hahn,Andreas Jung +12 more
TL;DR: TIMP-3 fulfils all important criteria for being a target gene in the mutator pathway and might be a factor of general importance for colorectal carcinogenesis.
Journal ArticleDOI
Lifestyle factors associated with inflammatory bowel disease: data from the Swiss IBD cohort study
Severin A Lautenschlager,Mamadou Pathe Barry,Gerhard Rogler,Luc Biedermann,Philipp Schreiner,Alexander Siebenhüner,Karim Abdelrahman,Gentiana Ademi,Patrick Aepli,Amman Thomas,Claudia Anderegg,Anca-Teodora Antonino,Eva Archanioti,Eviano Arrigoni,Diana Bakker de Jong,Bruno M. Balsiger,Polat Bastürk,Peter Bauerfeind,Andrea Fiorenzo Becocci,Dominique Belli,José M. Bengoa,Janek Binek,Mirjam Blattmann,Stephan Boehm,Tujana Boldanova,Jan Borovicka,Christian P. BellBraeggeri,Stephan Brand,Lukas Brügger,Simon F. Brunner,Patrick Bühr,Bernard Burnand,Sabine Burk,E. Burri,Sophie Buyse,Dahlia Thao Cao,Ove Carstens,Dominique H. Criblez,Sophie Cunningham,F. D'Angelo,Philippe de Saussure,Lukas Degen,Joakim Delarive,Christopher Doerig,Barbara Dora,Susann Drerup,Mara Egger,Ali Abdou El-Wafa,Matthias Engelmann,Jessica Ezri,Christian Felley,Markus Fliegner,Nicolas Fournier,Montserrat Fraga,Yannick Franc,Pascal Frey,Remus Frei,Michael Fried,Florian Froehlich,Raoul I. Furlano,Luca Garzoni,M. Geyer,L. Girard,Marc Girardin,Delphine Golay,Ignaz Good,U. Graf Bigler,Beat Gysi,Johannes Haarer,Marcel Halama,J. Haldemann,Pius Heer,Benjamin Heimgartner,Beat Helbling,Peter Hengstler,Denise Herzog,Cyrill Hess,Roxane Hessler,Klaas Heyland,Thomas A. Hinterleitner,Claudia Hirschi,Petr Hruz,Pascal Juillerat,Carolina A.J. Khalid-de Bakker,Stephan Kayser,Céline Keller,Christina Knellwolf(-Grieger),Christoph Knoblauch,Henrik Köhler,Rebekka Koller,Claudia Krieger-Grübel,Patrizia Künzler,Rachel Kusche,Frank Serge Lehmann,Andrew J. Macpherson,Michel H. Maillard,Michael Manz,Astrid Marot,Rémy Meier,Christa Meyenberger,Pamela Meyer,Pierre Michetti,Benjamin Misselwitz,Patrick Mosler,Christian Mottet,Christoph Müller,Beat Müllhaupt,Leilla Musso,Michaela Neagu,Cristina Nichita,Jan Hendrik Niess,Andreas Nydegger,Nicole Obialo,Diana Ollo,Cassandra Oropesa,Ulrich Peter,Daniel Peternac,Laëtitia Marie Petit,Valérie Pittet,Daniel Pohl,Marc Porzner,Claudia Preissler,Nadia Raschle,Ronald Rentsch,A. Restellini,Sophie Restellini,Jean-Pierre Richterich,Frédéric Ris,B Risti,Marc Alain Ritz,Nina Röhrich,Jean-Benoît Rossel,Vanessa Rueger,M Rusticeanu,Markus Sagmeister,Gaby Saner,Bernhard Sauter,Mikael Sawatzki,Michael Scharl,Martin Schelling,Susanne Schibli,Hugo Schlauri,Dominique Schluckebier,Daniel Josef Schmid,Sybille Schmid(-Uebelhart),J. F. Schnegg,Alain M. Schoepfer,Vivianne Seematter,Frank Seibold,Mariam Seirafi,Gian-Marco Semadeni,Arne Senning,Christiane Sokollik,Joachim Sommer,Johannes Spalinger,Holger Spangenberger,Philipp Stadler,Peter Staub,Dominic Staudenmann,Volker Stenz,Michael Steuerwald,Alex Straumann,Bruno M. Strebel,Andreas Stulz,Michael Christian Sulz,Aurora Tatu,Michela Tempia-Caliera,Joël Thorens,Kaspar Truninger,Radu Tutuian,Patric Urfer,Stephan R. Vavricka,F. Viani,J. Vögtlin,Roland von Känel,Dominique Vouillamoz,Rachel Vulliamy,P. Wiesel,Reiner Wiest,Stefan Wöhrle,Samuel Zamora,Silvan Zander,Tina Wylie,Jonas Zeitz,Dorothee Zimmermann +184 more
TL;DR: In this paper , the authors identify lifestyle factors that affect the onset of Crohn's disease and ulcerative colitis and show that there is a protective effect of physical activity on inflammatory bowel disease.