Marc S. Levin

TL;DR: The genetic basis of IBD, the genetic and cellular alterations associated with colitis-associated colon cancer, and the emerging role of the intestinal microbiota and other environmental factors will be reviewed.

TL;DR: A 20-fold increase in placental apoB mRNA concentrations during the last 48 hr of pregnancy suggests a specific role for this organ in maternal-fetal lipid transport immediately prior to parturition, and Pulse-labeling experiments using 21-day fetal tissue slices showed that the liver synthesizes both apOB-100 (B-PI) and apo B-48 (B -PIII) albeit in somewhat different ratios than the adult organ.

TL;DR: Computer-assisted comparative sequence analyses indicated that a region of internal homology spans its first two exons and that oligopeptide domains specified by these first twoExons exhibit significant homology to all other family members as well as to a portion of the all-trans-retinolbinding domain that has previously been defined in serum retinol binding protein.

TL;DR: It is suggested that both fetal as well as maternal CRBP II are required to ensure adequate delivery of vitamin A to the developing fetus when dietary vitamin A is limiting.

TL;DR: 19F NMR analysis of recombinant isotopically labeled proteins represents a sensitive new and useful method for monitoring retinoid flux between the CRBPs in vitro.