Marcel C. M. Rutten

TL;DR: The strain-based conditioning approach, using both prestrain and dynamic strains, offers new possibilities for bioreactor design and optimization of tissue properties towards a tissue-engineered aortic human heart valve replacement.

TL;DR: This work investigated the feasibility of determining IMR in humans and tested the hypothesis that microvascular resistance is independent of epicardial stenosis, and found that IMR is a specific index of microv vascular resistance when collateral flow is properly taken into account.

TL;DR: Tissue properties and mechanical behavior might allow for use as living aortic valve replacements in tissue-engineered heart valves based on human saphenous vein cells and a rapid degrading synthetic scaffold.

TL;DR: Using a suitable infusion catheter and a 0.014-inch sensor-tipped guidewire for measurement of coronary pressure and temperature, volumetric blood flow can be directly measured in selective coronary arteries during cardiac catheterization.

TL;DR: The model presented shows to be well suited to predict wave propagation through these straight and tapered vessels with viscoelastic wall properties and hereto can serve as a time-domain-based method to model wave propagation in the human arterial system.