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Marcos Lopez

Researcher at University of Valle

Publications -  41
Citations -  4339

Marcos Lopez is an academic researcher from University of Valle. The author has contributed to research in topics: Mitochondrion & Nitric oxide. The author has an hindex of 23, co-authored 41 publications receiving 3488 citations. Previous affiliations of Marcos Lopez include Medical College of Wisconsin & University of Akron.

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Journal ArticleDOI

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

Frank Weinberg, +9 more
- 11 May 2010 - 
TL;DR: It is reported that the major function of glucose metabolism for Kras-induced anchorage-independent growth, a hallmark of transformed cells, is to support the pentose phosphate pathway.
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Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications

Jacek Zielonka, +8 more
- 27 Jun 2017 - 
TL;DR: The physicochemical basis for mitochondrial accumulation of lipophilic cations, synthetic chemistry strategies to target compounds to mitochondria, mitochondrial probes, and sensors, and examples of mitochondrial targeting of bioactive compounds are described.
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Endothelial dysfunction and preeclampsia: role of oxidative stress

Lissette Sanchez-Aranguren, +3 more
- 10 Oct 2014 - 
TL;DR: Current literature from research showing the interplay between oxidative stress, ED and PE to the outcomes of current clinical trials aiming to prevent PE with antioxidant supplementation is reviewed.
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Direct oxidation of boronates by peroxynitrite: Mechanism and implications in fluorescence imaging of peroxynitrite

Adam Sikora, +4 more
- 15 Nov 2009 - 
TL;DR: It is shown that boronates react rapidly and stoichiometrically with peroxynitrite (ONOO(-)) to form stable hydroxy derivatives as major products to help develop a novel class of fluorescent probes for the detection and imaging of ONOO(-) formed in cellular and cell-free systems.
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A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds.

Balaraman Kalyanaraman, +7 more
- 01 Apr 2018 - 
TL;DR: This review focuses on the selective antiproliferative and cytotoxic effects of mitochondria-targeted therapeutics (MTTs) in cancer cells and how signaling molecules traditionally linked to tumor cell proliferation affect tumor metabolism and bioenergetics.