M
Maria-Belen Trujillo-Torralbo
Researcher at National Institutes of Health
Publications - 28
Citations - 1728
Maria-Belen Trujillo-Torralbo is an academic researcher from National Institutes of Health. The author has contributed to research in topics: COPD & Rhinovirus. The author has an hindex of 14, co-authored 26 publications receiving 1366 citations. Previous affiliations of Maria-Belen Trujillo-Torralbo include Medical Research Council & Imperial College London.
Papers
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Journal ArticleDOI
Effect of CRTH2 antagonism on the response to experimental rhinovirus infection in asthma: a pilot randomised controlled trial
Hugo Farne,Nicholas Glanville,Nicholas Johnson,Tata Kebadze,Julia Aniscenko,Eteri Regis,Jie Zhu,Maria-Belen Trujillo-Torralbo,Onn Min Kon,Patrick Mallia,A Toby Prevost,Michael R. Edwards,Sebastian L. Johnston,Aran Singanayagam,David Joshua Jackson,David Joshua Jackson +15 more
TL;DR: In this paper, the chemoattractant receptor-homologous molecule expressed on T helper type 2 cells (CRTH2) antagonist timapiprant improved lung function and asthma control, with evidence suggesting reduced exacerbations.
Proceedings ArticleDOI
Bacterial Infections Following Experimental Rhinovirus Infection In COPD
Patrick Mallia,Joseph Footitt,Maria-Belen Trujillo-Torralbo,Gregory Oleszkiewicz,Abbie Omolu,Marco Contoli,Simon D. Message,Alberto Papi,Sebastian L. Johnston,Onn Min Kon +9 more
Journal Article
Induction of cathelicidin (LL-37) in rhinovirus-induced COPD exacerbations
Rosa Sotero,Patrick Mallia,Joseph Footitt,Maria-Belen Trujillo-Torralbo,Tatiana Kebadze,Contoli Marco,Alberto Papi,Girolamo Pelaia,Rosario Maselli,Sebastian L. Johnston +9 more
TL;DR: LL-37 in sputum and BAL following rhinovirus infection correlates with inflammatory cells, pro-inflammatory cytokines and virus load, and further studies are required to determine whether LL-37 contributes to neutrophilic inflammation in virus-induced exacerbations or is a component of the anti-viral innate immune response.
Journal Article
Rhinovirus infection upregulates pentraxin-3 in smokers and COPD patients
Joseph Footitt,Patrick Mallia,Sotero Rosa,Maria-Belen Trujillo-Torralbo,Tatiana Kebadze,Marco Contoli,Alberto Papi,Onn Min Kon,Rosario Maselli,Sebastian L. Johnston +9 more
TL;DR: PTX3 is likely to contribute to the inflammatory response in virus-induced COPD exacerbations and may be both a potential biomarker and therapeutic target in COPD.
Proceedings ArticleDOI
Airway glucose in COPD exacerbations
Jessica Webber,John Tregonning,Maria-Belen Trujillo-Torralbo,Maria Adelaide Calderazzo,Richard J. Hewitt,Hugo Farne,Joseph Footitt,PL Molyneaux,Sebastian L. Johnston,Patrick Mallia +9 more
TL;DR: This is the first in vivo evidence linking AG with airway inflammation and bacterial infections in COPD, and Therapies that reduce levels of AG have potential as non-antibiotic treatments to prevent bacterial infections.