M
Maria Picchio
Researcher at Vita-Salute San Raffaele University
Publications - 253
Citations - 9960
Maria Picchio is an academic researcher from Vita-Salute San Raffaele University. The author has contributed to research in topics: Prostate cancer & Positron emission tomography. The author has an hindex of 50, co-authored 220 publications receiving 9070 citations. Previous affiliations of Maria Picchio include National Research Council & Thomas Jefferson University.
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Journal ArticleDOI
Early lung-cancer detection with spiral CT and positron emission tomography in heavy smokers: 2-year results.
Ugo Pastorino,Massimo Bellomi,C. Landoni,Elvio De Fiori,Patrizia Arnaldi,Maria Picchio,Giuseppe Pelosi,Peter Boyle,F. Fazio +8 more
TL;DR: Combined use of low-dose spiral CT and selective PET effectively detects early lung cancer in high-risk individuals in a large cohort of high- risk volunteers.
Journal ArticleDOI
Physical performance of the new hybrid PET∕CT Discovery-690.
Valentino Bettinardi,Luca Presotto,E. Rapisarda,Maria Picchio,Luigi Gianolli,Maria Carla Gilardi +5 more
TL;DR: The Discovery-690 shows very good PET physical performance for all the standard NEMA NU-2-2007 measurements and the new reconstruction algorithms available for PET data (TOF and PSF) allow further improvements of the D-690 image quality performance both qualitatively and quantitatively.
Journal Article
Hypoxia-Specific Tumor Imaging with 18F-Fluoroazomycin Arabinoside
Morand Piert,Hans Jürgen Machulla,Maria Picchio,Gerald Reischl,Sybille Ziegler,Piyush Kumar,Hans-Jürgen Wester,Roswitha Beck,Alexander J.B. McEwan,Leonard I. Wiebe,Markus Schwaiger +10 more
TL;DR: (18)F-FAZA shows superior biokinetics and is, thus, a promising PET tracer for the visualization of tumor hypoxia and also verified a Hypoxia-specific uptake mechanism for (18)f-FAza in murine tumor models.
Journal ArticleDOI
Value of [11C]choline-Positron Emission Tomography for Re-Staging Prostate Cancer: A Comparison With [18F]fluorodeoxyglucose-Positron Emission Tomography
Maria Picchio,Cristina Messa,C. Landoni,Luigi Gianolli,Sandro Sironi,M. Brioschi,Mario Matarrese,Deliu Victor Matei,F. De Cobelli,A. Del Maschio,Francesco Rocco,P. Rigatti,F. Fazio +12 more
TL;DR: 11C]choline-PET seems to be useful for re-staging prostatectomy cases with increasing serum PSA levels and is superior to [18F]fluorodeoxyglucose-PET and complementary to conventional imaging but with the advantage of staging disease at a single step.
Journal ArticleDOI
Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27.
Rossano Cesari,Eric S. Martin,George A. Calin,Francesca Pentimalli,Roberta Bichi,Holly McAdams,Francesco Trapasso,Alessandra Drusco,Masayoshi Shimizu,Valeria Masciullo,Giuseppina D'Andrilli,Giovanni Scambia,Maria Picchio,Hansjuerg Alder,Andrew K. Godwin,Carlo M. Croce +15 more
TL;DR: The loss of heterozygosity observed at chromosome 6q25–q26 may contribute to the initiation and/or progression of cancer by inactivating or reducing the expression of the Parkin gene, another example of a large tumor suppressor gene, like FHIT and WWOX, located at a common fragile site.