Cyanines during the 1990s: A Review

Anti-cancer drugs

On the medicinal chemistry of gold complexes as anticancer drugs

Flipping the light switch 'on'--the design of sensor molecules that show cation-induced fluorescence enhancement with heavy and transition metal ions.

The coordination chemistry of guanidines and guanidinates

A series of seven 2-cinnamoyl-1,3-indandiones and their metal(II) complexes were synthesized and characterized by means of spectroscopic (IR, NMR, electron absorption and emission spectroscopy) and/or single-crystal X-ray diffraction methods. The optical spectra of the organic compounds show very strong absorption in the visible region and weak fluorescence with moderate to strong Stokes shift. The effect of concentration, water addition and metal ion complexation on the optical properties was also studied. In search of potential practical application, the complexation of 2-cinnamoyl-1,3-indandiones with metal(II) ions was investigated. A series of non-charged complexes with Cu(II), Cd(II), Zn(II), Co(II) and Ni(II) was isolated and analyzed by elemental analyses and IR. Most of the complexes show presence of water molecules, most probably coordinated to the metal ion, thus forming octahedral geometry. For the paramagnetic Cu(II) complexes a distorted, flattened tetrahedral structure is proposed, basing on the EPR data. The optical properties of the metal complexes, however, do not differ appreciably from those of the free ligands.

Structure and properties of a series of 2-cinnamoyl-1,3-indandiones and their metal complexes

Reactivity of vanadium(V) polymeric and monomeric forms in complex formation with p-phenetidine

Data on the ability of the important bioligands creatinine and creatine to form various types of complexes with different metal ions are summarized. The crucial role of the nature of the reaction medium in complex formation with these ligands is emphasized. The conditions for obtaining paramagnetic oligomeric platinum complexes of the “platinum blue” type (resulting from multistep redox and coordination processes) are presented.

Coordination Properties of the Bioligands Creatinine and Creatine in Various Reaction Media

Pd(creat)2Cl2·2H2O crystallizes in space group P&1macr; with a= 7.257(2), b= 8.159(2), c= 14.640(2) A, f =73.97(2), g =77.0(1), u =72.22(2)°, Z=2, and represents a new allotropic form of this compound. Pd atoms have planar fourfold coordination of N and Cl atoms in trans configuration. Creatinine moieties are coordinated to the Pd atoms via endocyclic N atoms and their essential planarity causes significant delocalization of electron density. The structure is stabilized by a system of weak hydrogen bonds involving interstitial water molecules and creatinine amino-groups.

Mariana Mitewa

Papers

Structure and properties of a series of 2-cinnamoyl-1,3-indandiones and their metal complexes

Reactivity of vanadium(V) polymeric and monomeric forms in complex formation with p-phenetidine

Coordination Properties of the Bioligands Creatinine and Creatine in Various Reaction Media

Crystal Structure of a New Allotropic Form of trans-Pd(Creat)2Cl2·2H2O

EPR study on Cr(V)-oxalic acid complexes in nonaqueous medium