M
Marianela Veronica Carabajal
Researcher at National Scientific and Technical Research Council
Publications - 4
Citations - 80
Marianela Veronica Carabajal is an academic researcher from National Scientific and Technical Research Council. The author has contributed to research in topics: Antigen & Bacterial outer membrane. The author has an hindex of 4, co-authored 4 publications receiving 65 citations.
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Journal ArticleDOI
A bacterial protease inhibitor protects antigens delivered in oral vaccines from digestion while triggering specific mucosal immune responses
Andrés E. Ibañez,Lorena M. Coria,Marianela Veronica Carabajal,María Victoria Delpino,Gabriela Sofía Risso,Paula L. González Cobiello,Jimena Rinaldi,Paula Barrionuevo,Laura Bruno,Fernanda M. Frank,Sebastián Klinke,Fernando Alberto Goldbaum,Gabriel Briones,Guillermo H. Giambartolomei,Karina A. Pasquevich,Juliana Cassataro +15 more
TL;DR: A bacterial protease inhibitor from Brucella spp.
Journal ArticleDOI
U-Omp19 from Brucella abortus Is a Useful Adjuvant for Vaccine Formulations against Salmonella Infection in Mice
Gabriela Sofía Risso,Marianela Veronica Carabajal,Laura Bruno,Andrés E. Ibañez,Lorena M. Coria,Karina A. Pasquevich,Seung-Joo Lee,Stephen J. McSorley,Gabriel Briones,Juliana Cassataro +9 more
TL;DR: This study demonstrates that U-Omp19, a bacterial protease inhibitor with immunostimulatory features, coadministered with Salmonella antigens by the oral route, enhances mucosal and systemic immune responses in mice and supports the potential of U- Omp19 as a suitable adjuvant in oral vaccine formulations against mucosal pathogens requiring T helper (Th)1–Th17 protective immune responses.
Journal ArticleDOI
A Brucella spp. Protease Inhibitor Limits Antigen Lysosomal Proteolysis, Increases Cross-Presentation, and Enhances CD8+ T Cell Responses.
Lorena M. Coria,Andrés E. Ibañez,Mercedes Tkach,Florencia Sabbione,Laura Bruno,Marianela Veronica Carabajal,Paula Mercedes Berguer,Paula Barrionuevo,Roxana Schillaci,Analía Silvina Trevani,Guillermo H. Giambartolomei,Karina A. Pasquevich,Juliana Cassataro +12 more
TL;DR: Results indicate that a cysteine protease inhibitor from bacterial origin could be a suitable component of vaccine formulations against tumors, and U-Omp19 coadministration, increasing survival of mice in a murine melanoma challenge model.
Journal ArticleDOI
Omp19 Enables Brucella abortus to Evade the Antimicrobial Activity From Host's Proteolytic Defense System.
Karina A. Pasquevich,Marianela Veronica Carabajal,Francisco Fernando Guaimas,Laura Bruno,Mara S. Roset,Lorena M. Coria,Diego A. Rey Serrantes,Diego J. Comerci,Juliana Cassataro +8 more
TL;DR: This work describes for the first time a physiological function of B. abortus Omp19 that enables Brucella to better thrive in the harsh gastrointestinal tract, where protection from proteolytic degradation can be a matter of life or death, and afterwards invade the host and bypass intracellular proteases to establish the chronic infection.