M
Marie-Jo Brion
Researcher at University of Queensland
Publications - 36
Citations - 3577
Marie-Jo Brion is an academic researcher from University of Queensland. The author has contributed to research in topics: Offspring & Pregnancy. The author has an hindex of 20, co-authored 34 publications receiving 2906 citations. Previous affiliations of Marie-Jo Brion include Murdoch University & Garvan Institute of Medical Research.
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Journal ArticleDOI
The Medical Genome Reference Bank: a whole-genome data resource of 4000 healthy elderly individuals. Rationale and cohort design
Paul Lacaze,Mark Pinese,Mark Pinese,Warren Kaplan,Andrew Stone,Marie-Jo Brion,Robyn L. Woods,Martin McNamara,John J McNeil,Marcel E. Dinger,Marcel E. Dinger,David Thomas,David Thomas +12 more
TL;DR: The Medical Genome Reference Bank is described, a large-scale comprehensive whole-genome data set of healthy elderly individuals that provides an accessible data resource for health-related research and clinical genetics and a powerful platform for studying the genetics of healthy ageing.
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Commentary: Assessing the impact of breastfeeding on child health: where conventional methods alone fall short for reliably establishing causal inference.
TL;DR: It is thus becoming increasingly apparent that combining conventional approaches with additional methods of testing causal inference are required to establish the long-term effects of breastfeeding and other developmental exposures on later life outcomes.
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Beyond the Single SNP: Emerging Developments in Mendelian Randomization in the “Omics” Era
Marie-Jo Brion,Marie-Jo Brion,Beben Benyamin,Peter M. Visscher,Peter M. Visscher,George Davey Smith +5 more
TL;DR: This review discusses new developments, ranging from the application of multiple genetic markers and the use of summary statistic data to MR approaches in the “omics” age, as well as novel extensions to the traditional single-SNP MR approach.
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Mining, visualizing and comparing multidimensional biomolecular data using the Genomics Data Miner (GMine) Web-Server.
Carla Proietti,Martha Zakrzewski,Thomas S. Watkins,Bernard Berger,Shihab Hasan,Shihab Hasan,Champa N. Ratnatunga,Marie-Jo Brion,Peter D. Crompton,John J. Miles,John J. Miles,Denise L. Doolan,Denise L. Doolan,Lutz Krause,Lutz Krause +14 more
TL;DR: Using GMine, proteome microarray data of host antibody response against Plasmodium falciparum supports the hypothesis that immunity to malaria is a higher-order phenomenon related to a pattern of responses and not attributable to any single antigen.
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Commentary: Can maternal-paternal comparisons contribute to our understanding of maternal pre-pregnancy obesity and its association with offspring cognitive outcomes?
TL;DR: Ass associations of maternal pre-pregnancy obesity with lower infant cognitive development scores in two European cohorts, RHEA and INMA, are reported and results were replicated across the two cohorts, reflecting two important methodological strengths of the paper.