Marie-Louise Smith

TL;DR: It is proposed that in Alzheimer disease, AGEs in paired helical filament tau can induce oxidant stress, thereby promoting neuronal dysfunction, and being ideal substrates for nonenzymatic glycation.

TL;DR: In this article, the authors present a new synthesis of existing data sets for the northeastern United States, intended to answer a single question: Is N deposition altering the N status of forest ecosystems in this region?

TL;DR: It is concluded that webcams offer an inexpensive means by which phenological changes in the canopy state can be quantified and a network of cameras could offer a novel opportunity to implement a regional or national phenology monitoring program.

TL;DR: To increase the level of secreted mEGF, a synthetic secretion cassette encoding the alpha-factor prepro leader peptide from Saccharomyces cerevisiae fused to mouse epidermal growth factor was constructed and a method for rapidly screening large numbers of P. pastoris transformants for the presence of many copies of a foreign gene was developed.

TL;DR: In this article, the authors examined relationships among canopy chemistry, nitrogen cycling, and soil carbon:nitrogen ratios across 30 forested stands in the White Mountains of New Hampshire and found that rates of net N mineralization and net nitrification were correlated across all plots, across all species, and were broadly grouped into two disturbance categories: those that were historically affected by intensive logging and/or fire and those that experienced minimal human disturbance.