M
Marie-Paule Wautier
Researcher at French Institute of Health and Medical Research
Publications - 42
Citations - 2425
Marie-Paule Wautier is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: RAGE (receptor) & Endothelial stem cell. The author has an hindex of 23, co-authored 39 publications receiving 2229 citations. Previous affiliations of Marie-Paule Wautier include University of Bonn & University of Paris.
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Journal ArticleDOI
Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE.
Marie-Paule Wautier,O. Chappey,Stefano Corda,David M. Stern,Ann Marie Schmidt,Jean-Luc Wautier +5 more
TL;DR: Findings underscore a central role of NADPH oxidase in AGE-RAGE-mediated generation of ROS and provide a mechanism for altered gene expression in A GE-related disorders.
Journal ArticleDOI
AGEs bind to mesothelial cells via RAGE and stimulate VCAM-1 expression
Eric Boulanger,Marie-Paule Wautier,Marie-Paule Wautier,JL Wautier,JL Wautier,Bernadette Boval,Bernadette Boval,Yves Panis,Yves Panis,Nicolas Wernert,Nicolas Wernert,Pierre-Marie Danze,Pierre-Marie Danze,Philippe Dequiedt,Philippe Dequiedt +14 more
TL;DR: The AGE-RAGE interaction resulted in HPMC activation, which may promote local inflammation, and thus is implicated in the peritoneal injury found in long-term PD patients.
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Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic mice.
Radia Tamarat,Jean-Sébastien Silvestre,Maya S. P. Huijberts,Joelle Benessiano,Téni G. Ebrahimian,Micheline Duriez,Marie-Paule Wautier,J.-L. Wautier,Bernard I. Levy +8 more
TL;DR: In this article, Aminoguanidine (50 mg/kg) and streptozotocin (40 mg/ kg) were used to prevent advanced glycation end products (AGEs) formation in diabetic mice.
Journal ArticleDOI
Increased adhesion to endothelial cells of erythrocytes from patients with polycythemia vera is mediated by laminin alpha5 chain and Lu/BCAM.
Marie-Paule Wautier,Wassim El Nemer,Pierre Gane,Jean-Didier Rain,Jean-Pierre Cartron,Yves Colin,Caroline Le Van Kim,Jean-Luc Wautier +7 more
TL;DR: Results indicate that JAK2 mutation might be linked to Lu/BCAM modification and increased RBC adhesiveness, which may be a factor favoring thrombosis in PV.
Journal ArticleDOI
JAK2V617F activates Lu/BCAM-mediated red cell adhesion in polycythemia vera through an EpoR-independent Rap1/Akt pathway.
Maria De Grandis,Marie Cambot,Marie-Paule Wautier,Bruno Cassinat,Christine Chomienne,Yves Colin,Jean-Luc Wautier,Jean-Luc Wautier,Caroline Le Van Kim,Wassim El Nemer +9 more
TL;DR: In this paper, the authors investigated the mechanism responsible for Lu/BCAM phosphorylation in the presence of JAK2V617F using HEL and BaF3 cell lines as well as RBCs from patients with polycythemia vera.