R
Radia Tamarat
Researcher at Institut de radioprotection et de sûreté nucléaire
Publications - 54
Citations - 4461
Radia Tamarat is an academic researcher from Institut de radioprotection et de sûreté nucléaire. The author has contributed to research in topics: Mesenchymal stem cell & Angiogenesis. The author has an hindex of 24, co-authored 49 publications receiving 4124 citations. Previous affiliations of Radia Tamarat include University of Paris & French Institute of Health and Medical Research.
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Journal ArticleDOI
Plasticity of Human Adipose Lineage Cells Toward Endothelial Cells Physiological and Therapeutic Perspectives
Valérie Planat-Benard,Jean-Sébastien Silvestre,Béatrice Cousin,Mireille André,Maryse Nibbelink,Radia Tamarat,Michel Clergue,Carole Manneville,Corinne Saillan-Barreau,Micheline Duriez,Alain Tedgui,Bernard I. Levy,Luc Pénicaud,Louis Casteilla +13 more
TL;DR: This study demonstrates, for the first time, that adipocytes and endothelial cells have a common progenitor, and highlights the concept that adipose lineage cells represent a suitable new cell source for therapeutic angiogenesis in ischemic disease.
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Cell Therapy Based on Adipose Tissue-Derived Stromal Cells Promotes Physiological and Pathological Wound Healing
Teni Ebrahimian,F. Pouzoulet,Claire Squiban,V. Buard,Mireille André,Béatrice Cousin,P. Gourmelon,M. Benderitter,Louis Casteilla,Radia Tamarat +9 more
TL;DR: In situ interphase fluorescence hybridization showed that a small number of ADSCs have the potential to fuse with endogenous keratinocytes, and ADSCs participate in dermal wound healing in physiological and pathological conditions by their ability to promote reepithelialization and angiogenesis.
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Lactadherin promotes VEGF-dependent neovascularization
Jean-Sébastien Silvestre,Clotilde Théry,Ghislaine Hamard,Jacques Boddaert,Barbara Aguilar,Alain Delcayre,Christophe Houbron,Radia Tamarat,Olivier Blanc-Brude,Sylvia Heeneman,Michel Clergue,Micheline Duriez,Régine Merval,Bernard I. Levy,Alain Tedgui,Sebastian Amigorena,Ziad Mallat +16 more
TL;DR: It is shown that an integrin-binding protein initially described in milk-fat globule, MFG-E8 (also known as lactadherin), is expressed in and around blood vessels and has a crucial role in VEGF-dependent neovascularization in the adult mouse.
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Angiotensin II angiogenic effect in vivo involves vascular endothelial growth factor- and inflammation-related pathways.
TL;DR: In an in vivo model, Ang II induced angiogenesis through AT1 receptor, which involved activation of VEGF/eNOS-related pathway and of the inflammatory process, and was associated with an increase in vascular endothelial growth factor, endothelial nitric oxide, and cyclooxygenase-2 levels.
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Antiangiogenic Effect of Interleukin-10 in Ischemia-Induced Angiogenesis in Mice Hindlimb
Jean-Sébastien Silvestre,Ziad Mallat,Micheline Duriez,Radia Tamarat,Michel Bureau,Daniel Scherman,Nicolas Duverger,Didier Branellec,Alain Tedgui,Bernard I. Levy +9 more
TL;DR: The antiangiogenic effect of IL-10 associated with the downregulation of VEGF expression is underscored and a role for the inflammatory balance in the modulation of ischemia-induced angiogenesis is suggested.