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Mariell Jessup

Researcher at American Heart Association

Publications -  269
Citations -  80056

Mariell Jessup is an academic researcher from American Heart Association. The author has contributed to research in topics: Heart failure & Transplantation. The author has an hindex of 69, co-authored 261 publications receiving 72097 citations. Previous affiliations of Mariell Jessup include Temple University & University of Pittsburgh.

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Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID) A Phase 2 Trial of Intracoronary Gene Therapy of Sarcoplasmic Reticulum Ca2+-ATPase in Patients With Advanced Heart Failure

TL;DR: The Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease study demonstrated safety and suggested benefit of adeno-associated virus type 1/sarcoplasmic reticulum Ca2+-ATPase in advanced heart failure, supporting larger confirmatory trials.
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INTERMACS Profiles of Advanced Heart Failure: The Current Picture

TL;DR: Patients considered for mechanical circulatory support can now be classified using the 7 profiles plus 3 modifiers developed through INTERMACS, and understanding these profiles and their impact on outcome should help to better select patients and therapies in the advanced stages of disease.