Kathryn J. Ruddy

TL;DR: A genome-wide association study of breast cancer in 122,977 cases and 105,974 controls of European ancestry and 14,068 cases and 13,104 controls of East Asian ancestry finds that heritability of Breast cancer due to all single-nucleotide polymorphisms in regulatory features was 2–5-fold enriched relative to the genome- wide average.

TL;DR: Recommendations for prevention and monitoring of cardiac dysfunction in survivors of adult-onset cancers were developed by an expert panel with multidisciplinary representation using a systematic review of meta-analyses, randomized clinical trials, observational studies, and clinical experience.

TL;DR: This PRS, optimized for prediction of estrogen receptor (ER)-specific disease, from the largest available genome-wide association dataset is developed and empirically validated and is a powerful and reliable predictor of breast cancer risk that may improve breast cancer prevention programs.

TL;DR: In this article, a review article describes available data regarding adherence and persistence among patients with cancer, as well as studies of interventions to improve adherence, which ranged from 16% to 100% with different therapies and different methods of measurement.

TL;DR: Greater concern about fertility was associated with younger age, nonwhite race, not having children, and receipt of chemotherapy, while only a minority of women currently pursue available fertility preservation strategies in this setting.