M
Marina Katerelos
Researcher at University of Melbourne
Publications - 42
Citations - 1628
Marina Katerelos is an academic researcher from University of Melbourne. The author has contributed to research in topics: AMPK & AMP-activated protein kinase. The author has an hindex of 21, co-authored 39 publications receiving 1522 citations. Previous affiliations of Marina Katerelos include St. Vincent's Health System & Austin Hospital.
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Journal ArticleDOI
The alpha-1,3-galactosyltransferase knockout mouse. Implications for xenotransplantation.
R. G. Tearle,M. J. Tange,Z. L. Zannettino,Marina Katerelos,Trixie A. Shinkel,B. J. W. Van Denderen,A. J. Lonie,I. Lyons,Mark B. Nottle,T. Cox,C. Becker,A. Peura,P. L. Wigley,Robert J. Crawford,Allan J. Robins,Martin J. Pearse,Anthony J F D'Apice +16 more
TL;DR: These mice confirm the importance of the galactose alpha(1,3)-galactose epitope in human xenoreactivity and the logic of continuing efforts to generate pigs that lack this epitope as a source of donor organs.
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Array-Based Gene Discovery with Three Unrelated Subjects Shows SCARB2/LIMP-2 Deficiency Causes Myoclonus Epilepsy and Glomerulosclerosis
Samuel F. Berkovic,Samuel F. Berkovic,Leanne M. Dibbens,Leanne M. Dibbens,Alicia Oshlack,Jeremy D. Silver,Jeremy D. Silver,Marina Katerelos,Danya F. Vears,Danya F. Vears,Renate Lüllmann-Rauch,Judith Blanz,Ke Wei Zhang,Jim Stankovich,Jim Stankovich,Renate M Kalnins,John P. Dowling,Eva Andermann,Frederick Andermann,Enrico Faldini,Rudi D'Hooge,Lata Vadlamudi,Lata Vadlamudi,Richard A L Macdonell,Bree L. Hodgson,Marta A. Bayly,Judy Savige,John C. Mulley,John C. Mulley,Gordon K. Smyth,David A. Power,Paul Saftig,Melanie Bahlo +32 more
TL;DR: The heterogeneous pathology in the kidney and brain suggests that SCARB2/Limp2 has pleiotropic effects that may be relevant to understanding the pathogenesis of other forms of glomerulosclerosis or collapse and myoclonic epilepsies.
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Vascular endothelial growth factor is a survival factor for renal tubular epithelial cells.
TL;DR: Immunohistochemical staining using a variety of antibodies showed expression of both VEGF receptors in normal rat renal tubules in vivo, and data suggest that V EGF may act as a survival factor for renal tubular epithelium in vivo.
Journal ArticleDOI
Regulation of the renal-specific Na+–K+–2Cl− co-transporter NKCC2 by AMP-activated protein kinase (AMPK)
Scott A Fraser,Ignacio Gimenez,Natasha Cook,Ian G. Jennings,Marina Katerelos,Frosa Katsis,Vicki Levidiotis,Bruce E. Kemp,Bruce E. Kemp,David A. Power +9 more
TL;DR: A novel phosphorylation site is identified that maintains NKCC2-mediated transport under isotonic or basal conditions and the metabolic-sensing kinase, AMPK, is able to phosphorylate this site, potentially linking the cellular energy state with changes in co-transporter activity.
Journal ArticleDOI
Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin
Mardiana Lee,Marina Katerelos,Kurt Gleich,Sandra Galic,Bruce E. Kemp,Peter F Mount,David A. Power +6 more
TL;DR: It is indicated that reduced phosphorylation of ACC after renal injury contributes to the development of TIF, and that phosphorylated of ACC is required for metformin's antifibrotic action in the kidney.