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Marina Vivarelli

Researcher at Boston Children's Hospital

Publications -  109
Citations -  5394

Marina Vivarelli is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 31, co-authored 80 publications receiving 3482 citations. Previous affiliations of Marina Vivarelli include University of Rome Tor Vergata.

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Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference

TL;DR: Recommendations for best treatment strategies were discussed at length, providing the evidence base underpinning current treatment options, and knowledge gaps were identified and a prioritized research agenda was proposed to resolve outstanding controversial issues.
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Minimal Change Disease

TL;DR: In a substantial number of patients the disease is recurrent and requires long-term immunosuppression, with significant morbidity because of side effects, recent therapeutic advances, such as the use of anti-CD20 antibodies, have provided long- term remission off-therapy and suggest new hypotheses for disease pathogenesis.
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Impaired skeletal development in interleukin-6-transgenic mice: a model for the impact of chronic inflammation on the growing skeletal system.

TL;DR: Chronic overexpression of IL-6 alone induces a skeletal phenotype closely resembling growth and skeletal abnormalities observed in children with chronic inflammatory diseases, pointing to IL- 6 as a pivotal mediator of the impact of chronic inflammation on postnatal skeletal development.