M
Marites P. Melancon
Researcher at University of Texas MD Anderson Cancer Center
Publications - 78
Citations - 3397
Marites P. Melancon is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Medicine & Irreversible electroporation. The author has an hindex of 24, co-authored 63 publications receiving 2910 citations. Previous affiliations of Marites P. Melancon include GE Healthcare & University of Texas at Austin.
Papers
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Journal ArticleDOI
A chelator-free multifunctional [64Cu]CuS nanoparticle platform for simultaneous micro-PET/CT imaging and photothermal ablation therapy.
Min Zhou,Rui Zhang,Miao Huang,Wei Lu,Shaoli Song,Shaoli Song,Marites P. Melancon,Mei Tian,Dong Liang,Chun Li +9 more
TL;DR: The combination of small diameter, strong NIR absorption, and integration of (64)Cu as a structural component makes these CuS NPs ideally suited for multifunctional molecular imaging and therapy.
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Cancer theranostics with near-infrared light-activatable multimodal nanoparticles.
TL;DR: An up-to-date review of the synthesis and characterization, functionalization, and in vitro and in vivo evaluation of NIR lightactivatable multifunctional nanostructures used for imaging and therapy is provided.
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In vitro and in vivo targeting of hollow gold nanoshells directed at epidermal growth factor receptor for photothermal ablation therapy
Marites P. Melancon,Wei Lu,Zhi Yang,Rui Zhang,Zhi Cheng,Andrew M. Elliot,Jason Stafford,Tammy Y. Olson,Jin Z. Zhang,Chun Li +9 more
TL;DR: The absence of silica core, the relatively small particle size and high tumor uptake, and the absence of cytotoxic surfactant required to stabilize other gold nanoparticles suggest that immuno-HAuNS have the potential to extend to in vivo molecular therapy.
Journal ArticleDOI
Effects of Photoacoustic Imaging and Photothermal Ablation Therapy Mediated by Targeted Hollow Gold Nanospheres in an Orthotopic Mouse Xenograft Model of Glioma
Wei Lu,Marites P. Melancon,Chiyi Xiong,Qian Huang,Andrew Elliott,Shaoli Song,Rui Zhang,Leo G. Flores,Juri G. Gelovani,Lihong V. Wang,Geng Ku,R. Jason Stafford,Chun Li +12 more
TL;DR: Results show the feasibility of using a single nanostructure for image-guided local tumor PTA therapy with photoacoustic molecular imaging, and significantly prolonged the survival of tumor-bearing mice.
Journal ArticleDOI
Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer
Jun Zhao,Xiaofei Wen,Xiaofei Wen,Li Tian,Tingting Li,Tingting Li,Chunyu Xu,Xiaoxia Wen,Marites P. Melancon,Sanjay Gupta,Baozhong Shen,Weiyi Peng,Chun Li +12 more
TL;DR: It is shown that, in mouse models, irreversible electroporation reverses the immunosuppressive microenvironment of PDAC resulting in increased and durable response when combined with PD1 checkpoint inhibition therapy.