M
Marius Pachitariu
Researcher at Howard Hughes Medical Institute
Publications - 54
Citations - 8467
Marius Pachitariu is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Visual cortex & Population. The author has an hindex of 28, co-authored 49 publications receiving 4592 citations. Previous affiliations of Marius Pachitariu include UCL Institute of Neurology & University College London.
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Journal ArticleDOI
Fully integrated silicon probes for high-density recording of neural activity
James J. Jun,Nicholas A. Steinmetz,Nicholas A. Steinmetz,Nicholas A. Steinmetz,Joshua H. Siegle,Daniel J. Denman,Marius Bauza,Brian Barbarits,Albert K. Lee,Costas A. Anastassiou,Costas A. Anastassiou,Alexandru Andrei,Cagatay Aydin,Mladen Barbic,Timothy J. Blanche,Vincent Bonin,João Couto,B. Dutta,Sergey L. Gratiy,Diego A. Gutnisky,Michael Häusser,Bill Karsh,Peter Ledochowitsch,Carolina Mora Lopez,Catalin Mitelut,Catalin Mitelut,Silke Musa,Michael S. Okun,Michael S. Okun,Michael S. Okun,Marius Pachitariu,Marius Pachitariu,Jan Putzeys,P. Dylan Rich,Cyrille Rossant,Cyrille Rossant,Wei-Lung Sun,Karel Svoboda,Matteo Carandini,Kenneth D. Harris,Kenneth D. Harris,Christof Koch,John O'Keefe,Timothy D. Harris +43 more
TL;DR: The fully integrated functionality and small size of Neuropixels probes allowed large populations of neurons from several brain structures to be recorded in freely moving animals and opens a path towards recording of brain-wide neural activity during behaviour.
Journal ArticleDOI
Cellpose: a generalist algorithm for cellular segmentation
TL;DR: This work introduces a generalist, deep learning-based segmentation method called Cellpose, which can precisely segment cells from a wide range of image types and does not require model retraining or parameter adjustments.
Journal ArticleDOI
Spontaneous behaviors drive multidimensional, brainwide activity.
Carsen Stringer,Marius Pachitariu,Nicholas A. Steinmetz,Charu Bai Reddy,Matteo Carandini,Kenneth D. Harris +5 more
TL;DR: In this article, the authors observed that spontaneous activity reliably encoded a high-dimensional latent state, which was partially related to the mouse's ongoing behavior and was represented not just in visual cortex but also across the forebrain.
Posted ContentDOI
Suite2p: beyond 10,000 neurons with standard two-photon microscopy
Marius Pachitariu,Carsen Stringer,Sylvia Schröder,Mario Dipoppa,L. Federico Rossi,Matteo Carandini,Kenneth D. Harris +6 more
TL;DR: Seat2p is introduced: a fast, accurate and complete pipeline that registers raw movies, detects active cells, extracts their calcium traces and infers their spike times, and recovers ~2 times more cells than the previous state-of-the-art method.
Posted ContentDOI
Kilosort: realtime spike-sorting for extracellular electrophysiology with hundreds of channels
TL;DR: Kilosort models the recorded voltage as a sum of template waveforms triggered on the spike times, allowing overlapping spikes to be identified and resolved and is an important step towards fully automated spike sorting of multichannel electrode recordings.