M
Mark A. Vickers
Researcher at University of Aberdeen
Publications - 88
Citations - 4082
Mark A. Vickers is an academic researcher from University of Aberdeen. The author has contributed to research in topics: Antigen & T cell. The author has an hindex of 29, co-authored 87 publications receiving 3703 citations. Previous affiliations of Mark A. Vickers include Aberdeen Royal Infirmary & Scottish National Blood Transfusion Service.
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Journal ArticleDOI
Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphoma
Neil Andrew Marshall,L. E. Christie,Laura R Munro,Dominic Culligan,Peter Johnston,Robert N. Barker,Mark A. Vickers +6 more
TL;DR: HLILs are highly enriched for regulatory T cells, which induce a profoundly immunosuppressive environment and so provide an explanation for the ineffective immune clearance of Hodgkin-Reed Sternberg cells.
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ABO(H) blood groups and vascular disease: a systematic review and meta-analysis.
TL;DR: An accurate calculation of risk would allow direct assessment of whether the effects of non‐O status on thrombosis risk are of the magnitude predicted by its effect on von Willebrand factor/FVIII levels.
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Genotype at a promoter polymorphism of the interleukin-6 gene is associated with baseline levels of plasma C-reactive protein.
Mark A. Vickers,Fiona Green,Catherine Terry,Bongani M. Mayosi,Cécile Julier,Mark Lathrop,Peter J. Ratcliffe,Hugh Watkins,Bernard Keavney +8 more
TL;DR: Baseline plasma CRP is a significantly heritable cardiovascular risk factor and levels are associated with genotype at the -174G/C polymorphism of the IL-6 gene, suggesting it arises from chromosomal proximity or identity of the typed polymorphism with a genetic variant influencing baseline CRP levels.
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Pulmonary and systemic effects of short-term inhalation exposure to ultrafine carbon black particles.
Peter S. Gilmour,A. Ziesenis,E.Rona Morrison,Mark A. Vickers,Ellen M Drost,Isobel Ford,Erwin Karg,Claudia Mossa,Andreas Schroeppel,George A. Ferron,Joachim Heyder,Michael Greaves,William MacNee,Ken Donaldson +13 more
TL;DR: There is a small but consistent significant proinflammatory effect of this exposure to ultrafine particles that is greater than the effect of the same exposure to fine CB, which was associated with significant increases in the total numbers of blood leukocytes.
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Prothrombotic genotypes are not associated with pre-eclampsia and gestational hypertension: Results from a large population-based study and systematic review
Elspeth Rona Morrison,Z. Miedzybrodzka,Doris M. Campbell,Neva E. Haites,B. J. Wilson,Mags Watson,Michael Greaves,Mark A. Vickers +7 more
TL;DR: There is little value in antenatal screening for prothrombotic polymorphisms to predict the development of pre-eclampsia or gestational hypertension, for all but cases of severe disease.