M
Mark S. Gresnigt
Researcher at University of Colorado Denver
Publications - 2
Citations - 51
Mark S. Gresnigt is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Inflammation & Interleukin. The author has an hindex of 2, co-authored 2 publications receiving 16 citations. Previous affiliations of Mark S. Gresnigt include Leibniz Association & Radboud University Nijmegen.
Papers
More filters
Journal ArticleDOI
The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity.
Giulio Cavalli,Isak W. Tengesdal,Isak W. Tengesdal,Mark S. Gresnigt,Mark S. Gresnigt,Mark S. Gresnigt,Travis Nemkov,Rob J.W. Arts,Jorge Domínguez-Andrés,Raffaella Molteni,Davide Stefanoni,Eleonora Cantoni,Laura Cassina,Silvia Giugliano,Kiki Schraa,Taylor S. Mills,Eric M. Pietras,Elan Z. Eisenmensser,Lorenzo Dagna,Alessandra Boletta,Angelo D'Alessandro,Leo A. B. Joosten,Mihai G. Netea,Mihai G. Netea,Charles A. Dinarello,Charles A. Dinarello +25 more
TL;DR: This article showed that recombinant Interleukin-37 (IL-37) abrogates the protective effects of trained immunity in vitro, as revealed by reduced host pro-inflammatory responses and survival to disseminated candidiasis.
Journal ArticleDOI
Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease.
Dennis M. de Graaf,Dennis M. de Graaf,Ralph J.A. Maas,Ralph J.A. Maas,Sanne P. Smeekens,Sanne P. Smeekens,Elan Z. Eisenmesser,Jasmina S. Redzic,Monique M. Helsen,Nicholas E. Powers,Suzhao Li,Vassili Kalabokis,Mark S. Gresnigt,Mark S. Gresnigt,Leo A. B. Joosten,Leo A. B. Joosten,Leo A. B. Joosten,Charles A. Dinarello,Charles A. Dinarello,Frank L. van de Veerdonk,Frank L. van de Veerdonk +20 more
TL;DR: Overall, IL-38 exhibits broad anti-inflammatory properties in models of systemic and local inflammation and therefore may be an effective cytokine therapy.