M
Mark S. Longtine
Researcher at Washington University in St. Louis
Publications - 49
Citations - 12348
Mark S. Longtine is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Septin & Septin ring. The author has an hindex of 28, co-authored 45 publications receiving 11569 citations. Previous affiliations of Mark S. Longtine include Oklahoma State University–Stillwater & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
Mark S. Longtine,Amos Mckenzie,Douglas J. Demarini,Nirav Shah,Achim Wach,Arndt Brachat,Peter Philippsen,John R. Pringle +7 more
TL;DR: A new set of plasmids that serve as templates for the PCR synthesis of fragments that allow a variety of gene modifications that should further facilitate the rapid analysis of gene function in S. cerevisiae.
Journal ArticleDOI
Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe
Jürg Bähler,Jian-Qiu Wu,Mark S. Longtine,Nirav Shah,Amos Mckenzie,Alexander B. Steever,Achim Wach,Peter Philippsen,John R. Pringle +8 more
TL;DR: A straightforward PCR‐based approach to the deletion, tagging, and overexpression of genes in their normal chromosomal locations in the fission yeast Schizosaccharomyces pombe, and a series of plasmids containing the kanMX6 module, which allows selection of G418‐resistant cells and thus provides a new heterologous marker for use in S. pom be.
Journal ArticleDOI
Bni1p, a Yeast Formin Linking Cdc42p and the Actin Cytoskeleton During Polarized Morphogenesis
Marie Evangelista,Kelly Blundell,Mark S. Longtine,Clinton J. Chow,Neil R. Adames,John R. Pringle,Matthias Peter,Charles Boone +7 more
TL;DR: The Saccharomyces cerevisiae BNI1 gene product (Bni1p) is a member of the formin family of proteins, which participate in cell polarization, cytokinesis, and vertebrate limb formation.
Journal ArticleDOI
The septins: Roles in cytokinesis and other processes
Mark S. Longtine,Douglas J. Demarini,Maria L. Valencik,Omayma S Al-Awar,Hanna Fares,Claudio De Virgilio,John R. Pringle +6 more
TL;DR: The septins are a novel family of proteins that were first recognized in yeast as proteins associated with the neck filaments and appear to be essential for this process in both fungal and animal cells.
Journal ArticleDOI
A protein interaction map for cell polarity development
Becky Drees,Bryan A. Sundin,Elizabeth Brazeau,Juliane P. Caviston,Guang-Chao Chen,Wei Guo,Keith G. Kozminski,Michelle W. Lau,John J. Moskow,Amy Hin Yan Tong,Laura R. Schenkman,Amos Mckenzie,Patrick Brennwald,Mark S. Longtine,Erfei Bi,Clarence S.M. Chan,Peter Novick,Charles Boone,John R. Pringle,Trisha N. Davis,Stanley Fields,David G. Drubin +21 more
TL;DR: A network of interactions that provide an integrated response of signaling proteins, the cytoskeleton, and organelles to the spatial cues that direct polarity development was revealed.