M
Markus Ringnér
Researcher at Science for Life Laboratory
Publications - 128
Citations - 18610
Markus Ringnér is an academic researcher from Science for Life Laboratory. The author has contributed to research in topics: Gene expression profiling & Breast cancer. The author has an hindex of 49, co-authored 119 publications receiving 15744 citations. Previous affiliations of Markus Ringnér include VTT Technical Research Centre of Finland & Lund University.
Papers
More filters
Journal ArticleDOI
Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing
Michael Bartoschek,Nikolay Oskolkov,Matteo Bocci,John Lövrot,Christer Larsson,Mikael Sommarin,Chris D. Madsen,David Lindgren,Gyula Pekar,Göran Karlsson,Markus Ringnér,Jonas Bergh,Åsa K. Björklund,Kristian Pietras +13 more
TL;DR: Improved resolution of the widely defined CAF population opens the possibility for biomarker-driven development of drugs for precision targeting of CAFs in clinical cohorts by association to metastatic disease.
Journal ArticleDOI
GOBO: Gene Expression-Based Outcome for Breast Cancer Online.
TL;DR: A multifunctional user-friendly online tool, GOBO is described, allowing a range of different analyses to be performed in an 1881-sample breast tumor data set, and a 51- sample breast cancer cell line set, both generated on Affymetrix U133A microarrays.
Journal ArticleDOI
Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns
Karolina Holm,Cecilia Hegardt,Johan Staaf,Johan Vallon-Christersson,Göran Jönsson,Håkan Olsson,Åke Borg,Markus Ringnér +7 more
TL;DR: It is found that breast cancers of the basal-like, luminal A and luminal B molecular subtypes harbour specific methylation profiles, suggesting that methylation may play an important role in the development of breast cancers.
Journal ArticleDOI
Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma.
Martin Lauss,Marco Donia,Katja Harbst,Rikke Andersen,Shamik Mitra,Frida Rosengren,Maryem Salim,Johan Vallon-Christersson,Therese Törngren,Anders Kvist,Markus Ringnér,Inge Marie Svane,Göran Jönsson +12 more
TL;DR: Predictive biomarkers, high non-synonymous mutation and high expressed neoantigen load, that associate with clinical benefit in ACT melanoma patients are identified.
Journal ArticleDOI
Gene expression profiling-based identification of molecular subtypes in stage IV melanomas with different clinical outcome.
Göran Jönsson,Christian Busch,Stian Knappskog,Jürgen Geisler,Hrvoje Miletic,Markus Ringnér,Johan R. Lillehaug,Åke Borg,Per Eystein Lønning +8 more
TL;DR: The data reveal a biologically based taxonomy of malignant melanomas with prognostic effect and support an influence of the antitumoral immune response on outcome.