M
Marta Canato
Researcher at University of Padua
Publications - 39
Citations - 1485
Marta Canato is an academic researcher from University of Padua. The author has contributed to research in topics: Calsequestrin & Skeletal muscle. The author has an hindex of 18, co-authored 36 publications receiving 1243 citations. Previous affiliations of Marta Canato include University of Rochester Medical Center.
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Journal ArticleDOI
DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass
Giulia Favaro,Vanina Romanello,Tatiana Varanita,Maria Andrea Desbats,Valeria Morbidoni,Caterina Tezze,Mattia Albiero,Marta Canato,Gaia Gherardi,Diego De Stefani,Cristina Mammucari,Bert Blaauw,Simona Boncompagni,Feliciano Protasi,Carlo Reggiani,Luca Scorrano,Leonardo Salviati,Marco Sandri +17 more
TL;DR: It is shown that genetic ablation of the pro-fission protein DRP1 leads to accumulation of abnormal mitochondria that induce muscle atrophy by altering Ca2+ homeostasis and cellular stress responses.
Journal ArticleDOI
Inducible activation of Akt increases skeletal muscle mass and force without satellite cell activation
Bert Blaauw,Marta Canato,Lisa Agatea,Luana Toniolo,Cristina Mammucari,Eva Masiero,Reimar Abraham,Marco Sandri,Stefano Schiaffino,Carlo Reggiani +9 more
TL;DR: An inducible transgenic model of muscle hypertrophy by short‐term Akt activation by showing that during a fast hyper‐trophic growth myonuclear domain can increase without compromising muscle performance can be concluded.
Journal ArticleDOI
Reorganized stores and impaired calcium handling in skeletal muscle of mice lacking calsequestrin-1
Cecilia Paolini,Marco Quarta,Alessandra Nori,Simona Boncompagni,Marta Canato,Pompeo Volpe,Paul D. Allen,Carlo Reggiani,Feliciano Protasi +8 more
TL;DR: Results demonstrate that CS1 is essential for the normal development of the SR and its calcium release units and for the storage and release of appropriate amounts of SR Ca2+.
Journal ArticleDOI
Anesthetic- and heat-induced sudden death in calsequestrin-1-knockout mice
Marco Dainese,Marco Quarta,Alla D. Lyfenko,Cecilia Paolini,Marta Canato,Carlo Reggiani,Robert T. Dirksen,Feliciano Protasi +7 more
TL;DR: In vitro studies indicate that CASQ1‐null muscle exhibits increased contractile sensitivity to temperature and caffeine, temperature‐dependent increases in resting Ca2+, and an increase in the magnitude of depolarization‐induced Ca2+ release.
Journal ArticleDOI
Massive alterations of sarcoplasmic reticulum free calcium in skeletal muscle fibers lacking calsequestrin revealed by a genetically encoded probe.
TL;DR: A targetable ratiometric FRET-based calcium indicator (D1ER Cameleon) allowed us to investigate SR Ca2+ dynamics and analyze the impact of calsequestrin (CSQ) on SR [Ca2+] in enzymatically dissociated flexor digitorum brevis muscle fibers from WT and CSQ-KO mice lacking isoform 1 or both isoforms.