M
Marta Terrile
Researcher at Royal College of Surgeons in Ireland
Publications - 12
Citations - 440
Marta Terrile is an academic researcher from Royal College of Surgeons in Ireland. The author has contributed to research in topics: Glioma & microRNA. The author has an hindex of 8, co-authored 11 publications receiving 382 citations. Previous affiliations of Marta Terrile include University College Dublin & University of Genoa.
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Journal ArticleDOI
Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time.
Marco Grossi,Marina Morgunova,Shane Cheung,Shane Cheung,Dimitri Scholz,Emer Conroy,Marta Terrile,Angela Panarella,Jeremy C. Simpson,William M. Gallagher,Donal F. O'Shea,Donal F. O'Shea +11 more
TL;DR: The design, synthesis and lysosome-responsive emission properties of a new NIR fluorophore are shown, which allows for direct translation to in vivo tumour imaging, which is successfully demonstrated using an MDA-MB-231 subcutaneous tumour model.
Journal ArticleDOI
Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer
Patrick O’Leary,Marta Terrile,Malgorzata Bajor,Pawel Gaj,Bryan T. Hennessy,Bryan T. Hennessy,Gordon B. Mills,Agnieszka Zagozdzon,Darran P. O'Connor,Donal J. Brennan,Kate Connor,Jane Li,Ana M. Gonzalez-Angulo,Han-Dong Sun,Jian-Xin Pu,Fredrik Pontén,Mathias Uhlén,Karin Jirström,Dominika Nowis,John Crown,Radoslaw Zagozdzon,William M. Gallagher +21 more
TL;DR: PRDX1 is shown to be an independent predictor of improved outcomes in ER-positive breast cancer and through its antioxidant function, PRDX1 may prevent oxidative stress-mediated ERα loss, thereby potentially contributing to maintenance of an ER- positive phenotype in mammary tumors.
Journal ArticleDOI
PDGF-B induces a homogeneous class of oligodendrogliomas from embryonic neural progenitors.
Irene Appolloni,Filippo Calzolari,Evelina Tutucci,Sara Caviglia,Marta Terrile,Giorgio Corte,Paolo Malatesta +6 more
TL;DR: Interestingly, it is found that PDGF‐B‐induced tumors harbor different proliferating cell populations, however only PDGFB‐overexpressing cells are tumorigenic, indicating that paracrine signaling from the tumor is unable to transform bystander cells.
Journal ArticleDOI
Tumor progression and oncogene addiction in a PDGF-B-induced model of gliomagenesis.
Filippo Calzolari,Irene Appolloni,Evelina Tutucci,Sara Caviglia,Marta Terrile,Giorgio Corte,Paolo Malatesta +6 more
TL;DR: It is formally demonstrated that PDGF-B-induced neoplasms undergo progression from nontumorigenic low-grade tumors toward highly malignant forms, and it is demonstrated that one of these lesions is represented by the down-regulation of the oncosuppressor Btg2.
Journal ArticleDOI
Discovery and visualization of miRNA–mRNA functional modules within integrated data using bicluster analysis
Kenneth Bryan,Marta Terrile,Isabella Bray,Raquel Domingo-Fernández,Karen M. Watters,Jan Koster,Rogier Versteeg,Raymond L. Stallings +7 more
TL;DR: This study is the first to apply the technique of biclustering to model functional modules within an integrated miRNA–mRNA association matrix, providing evidence of an extensive modular miRNA functional network and enabling characterization of miRNA function and dysregulation in disease.