M
Martha Skinner
Researcher at Boston University
Publications - 289
Citations - 17943
Martha Skinner is an academic researcher from Boston University. The author has contributed to research in topics: Amyloidosis & AL amyloidosis. The author has an hindex of 69, co-authored 289 publications receiving 16916 citations. Previous affiliations of Martha Skinner include Beth Israel Deaconess Medical Center & Veterans Health Administration.
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Journal ArticleDOI
A Report of Three Cases
William D. Travis,Robert Castile,Gordon Vawter,Harry Shwachman,Warren Warwick,Barbara A. Burke,Martha Skinner +6 more
TL;DR: It appears that secondary amyloidosis is emerging as a significant, although rare, complication of cystic fibrosis as greater numbers of these patients survive into adulthood.
Journal ArticleDOI
The Systemic Amyloidoses
TL;DR: Amyloidosis is not a single disease but a term for diseases that share a common feature: the extracellular deposition of pathologic insoluble fibrillar proteins in organs and tissues.
Journal ArticleDOI
High-Dose Melphalan and Autologous Stem-Cell Transplantation in Patients with AL Amyloidosis: An 8-Year Study
Martha Skinner,Vaishali Sanchorawala,David C. Seldin,Laura M. Dember,Rodney H. Falk,John L. Berk,Jennifer J. Anderson,Carl O'Hara,Kathleen T. Finn,Caryn A. Libbey,Janice F. Wiesman,Karen Quillen,Niall Swan,Daniel G. Wright +13 more
TL;DR: Analysis of consecutive patients with AL amyloidosis from 6 separate trials over 8 years shows that high-dose intravenous melphalan therapy combined with autologous stem-cell transplantation greatly improves duration of survival and ameliorates organ dysfunction.
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Repurposing Diflunisal for Familial Amyloid Polyneuropathy A Randomized Clinical Trial
John L. Berk,Ole B. Suhr,Laura Obici,Yoshiki Sekijima,Steven R. Zeldenrust,Taro Yamashita,Michael A. Heneghan,Peter D. Gorevic,William J. Litchy,Janice F. Wiesman,Erik Nordh,Manuel Corato,Alessandro Lozza,Andrea Cortese,Jessica Robinson-Papp,Theodore Colton,Denis Rybin,Alice Bisbee,Yukio Ando,Shu-ichi Ikeda,David C. Seldin,Giampaolo Merlini,Martha Skinner,Jeffery W. Kelly,Peter J. Dyck +24 more
TL;DR: Among patients with familial amyloid polyneuropathy, the use of diflunisal compared with placebo for 2 years reduced the rate of progression of neurological impairment and preserved quality of life.
Journal ArticleDOI
The clinical features of immunoglobulin light-chain (AL) amyloidosis with heart involvement.
Simon W Dubrey,K. Cha,Jennifer J. Anderson,Bindu Chamarthi,Johann Reisinger,Martha Skinner,Rodney H. Falk +6 more
TL;DR: It should be suspected in all patients with heart failure who have wall thickening on echo, normal chamber sizes, low EKG voltages and evidence suggesting a multisystem disease, and most frequently patients had features of multiorgan dysfunction; heavy proteinuria and features of mal absorption predominating in this respect.