M
Martine Moreau
Researcher at French Institute of Health and Medical Research
Publications - 26
Citations - 1885
Martine Moreau is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Scavenger receptor & Apolipoprotein B. The author has an hindex of 19, co-authored 26 publications receiving 1701 citations. Previous affiliations of Martine Moreau include Pierre-and-Marie-Curie University & University of Paris.
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Interleukin-8 mediates downregulation of tissue inhibitor of metalloproteinase-1 expression in cholesterol-loaded human macrophages : Relevance to stability of atherosclerotic plaque
TL;DR: Interleukin (IL)-8 may play a potential atherogenic role by inhibiting local TIMP-1 expression, thereby leading to an imbalance between MMPs and TIMPs at focal sites in the atherosclerotic plaque.
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Role of Scavenger Receptor Class B Type I in Hepatitis C Virus Entry: Kinetics and Molecular Determinants
Maria Teresa Catanese,Helenia Ansuini,Rita Graziani,Thierry Huby,Martine Moreau,Jonathan K. Ball,Giacomo Paonessa,Charles M. Rice,Riccardo Cortese,Alessandra Vitelli,Alfredo Nicosia +10 more
TL;DR: A specific and direct role for the identified residues in binding HCV and mediating virus entry is suggested and the hypothesis that new therapeutic strategies aimed at interfering with virus/SR-BI recognition are feasible is supported.
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The interaction of natural hepatitis C virus with human scavenger receptor SR-BI/Cla1 is mediated by ApoB-containing lipoproteins
TL;DR: The findings in hepatoma cell lines suggest that the interaction of HCV with human hepatocytes is equally mediated, at least in a part, by VLDL, and as such may represent an alternative pathway for infection.
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High-Avidity Monoclonal Antibodies against the Human Scavenger Class B Type I Receptor Efficiently Block Hepatitis C Virus Infection in the Presence of High-Density Lipoprotein
Maria Teresa Catanese,Rita Graziani,Thomas von Hahn,Martine Moreau,Thierry Huby,Giacomo Paonessa,Claudia Santini,Alessandra Luzzago,Charles M. Rice,Riccardo Cortese,Alessandra Vitelli,Alfredo Nicosia +11 more
TL;DR: It is demonstrated that SR-B1 is essential for infection with HCV produced in vitro and in vivo and the possible use of anti-SR-B 1 antibodies as therapeutic agents are suggested.
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Adenovirus-Mediated Overexpression of Tissue Inhibitor of Metalloproteinase-1 Reduces Atherosclerotic Lesions in Apolipoprotein E–Deficient Mice
Mustapha Rouis,C. Adamy,Nicolas Duverger,Philippe Lesnik,Philippe Horellou,Martine Moreau,Florence Emmanuel,Jean-Michel Caillaud,P. M. Laplaud,C. Dachet,M. J. Chapman +10 more
TL;DR: Investigation of adenovirus-mediated elevation in the circulating levels of human tissue inhibitor of MMP (TIMP-1) in atherosclerosis-susceptible apolipoprotein E-deficient mice revealed increases in collagen, elastin, and smooth muscle alpha-actin content in mice treated with rAd.