M
Marwa A. Saleh
Researcher at Al-Azhar University
Publications - 9
Citations - 181
Marwa A. Saleh is an academic researcher from Al-Azhar University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 2, co-authored 5 publications receiving 16 citations.
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Journal ArticleDOI
Anti-SARS-CoV-2 activities of tanshinone IIA, carnosic acid, rosmarinic acid, salvianolic acid, baicalein, and glycyrrhetinic acid between computational and in vitro insights
Dalia Elebeedy,Walid F. Elkhatib,Ahmed Kandeil,Aml Ghanem,Omnia Kutkat,Radwan Alnajjar,Radwan Alnajjar,Marwa A. Saleh,Ahmed I. Abd El Maksoud,Ingy Badawy,Ahmed A. Al-Karmalawy +10 more
TL;DR: Six compounds were screened for their anti-SARS-CoV-2 activities against both the spike (S) and main protease (Mpro) receptors using molecular docking studies and showed very promising virucidal activity with a most prominent inhibitory effect on viral adsorption rather than its replication.
Journal ArticleDOI
Design, synthesis, antiproliferative evaluation, and molecular docking study of new quinoxaline derivatives as apoptotic inducers and EGFR inhibitors
Eman A. Fayed,Yousry A. Ammar,Marwa A. Saleh,Ashraf H. Bayoumi,Amany Belal,Amany Belal,Ahmed B.M. Mehany,Ahmed Ragab +7 more
TL;DR: A new series of quinoxaline derivatives synthesized and pharmacologically evaluated against (HepG-2, HCT-116, and MCF-7) cell lines and revealed that it increases apoptotic cells and induced cell cycle arrest at pre-G1 and G2/M phases.
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Pharmacophore-linked pyrazolo[3,4-d]pyrimidines as EGFR-TK inhibitors: Synthesis, anticancer evaluation, pharmacokinetics, and in silico mechanistic studies
Ahmed A. Gaber,Ahmed El-Morsy,Ahmed El-Morsy,Farag F. Sherbiny,Farag F. Sherbiny,Ashraf H. Bayoumi,Kamal M. El-Gamal,Khaled El-Adl,Khaled El-Adl,Ahmed A. Al-Karmalawy,Rogy R. Ezz Eldin,Marwa A. Saleh,Hamada S. Abulkhair +12 more
TL;DR: In this article, the authors reported the design and synthesis of new hybrid molecules of the pyrazolo[3,4-d]pyrimidine scaffold linked with diverse pharmacophoric fragments with reported anticancer potential.
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Ligand-based design and synthesis of N'-Benzylidene-3,4-dimethoxybenzohydrazide derivatives as potential antimicrobial agents; evaluation by in vitro, in vivo, and in silico approaches with SAR studies
Rogy R Ezz Eldin,Marwa A. Saleh,Mohammad Hayal Alotaibi,Reem K Alsuair,Yahya A. Alzahrani,Feras Alshehri,Amany F. Mohamed,S. M. Hafez,Azza A. Althoqapy,Seham K Khirala,M.M. Amin,Y. A. F.,Azza H. AbdElwahab,Mohamed S Alesawy,Ayman Abo Elmaaty,Ahmed A. Al-Karmalawy +15 more
TL;DR: A series of new N'-benzylidene-3,4-dimethoxybenzohydrazide derivatives were designed and synthesised targeting the multidrug efflux pump (MATE) guided by the pharmacophoric features of the co-crystallized native inhibitor of the target protein.
Journal ArticleDOI
Quinoxaline Derivatives as a Promising Scaffold for Breast Cancer Treatment
TL;DR: According to Global Cancer Statistics 2021, female breast cancer has exceeded lung cancer as the most frequently diagnosed cancer and will remain so for the foreseeable future.