M
Mary B. O’Neill
Researcher at University of Wisconsin-Madison
Publications - 18
Citations - 528
Mary B. O’Neill is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Population & Allele. The author has an hindex of 8, co-authored 17 publications receiving 373 citations. Previous affiliations of Mary B. O’Neill include University of Washington & Pasteur Institute.
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Journal ArticleDOI
Engineered Chimeric Peptides as Antimicrobial Surface Coating Agents toward Infection-Free Implants
Hilal Yazici,Mary B. O’Neill,Turgay Kacar,Turgay Kacar,Brandon Ruf Wilson,Ersin Emre Oren,Ersin Emre Oren,Mehmet Sarikaya,Candan Tamerler,Candan Tamerler +9 more
TL;DR: A chimeric peptide with bifunctionality that both forms a robust solid-surface coating while presenting antimicrobial property and demonstrates significant improvement in reducing bacterial colonization onto titanium surfaces below the detectable limit.
Journal ArticleDOI
Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation
Ola Brønstad Brynildsrud,Caitlin S. Pepperell,Philip Noel Suffys,Louis Grandjean,Johana Monteserin,Nadia Debech,Jon Bohlin,Kristian Alfsnes,John O.-H. Pettersson,Ingerid Ørjansen Kirkeleite,Fatima Fandinho,Marcia Aparecida da Silva,João Perdigão,Isabel Portugal,Miguel Viveiros,Taane G. Clark,Maxine Caws,Maxine Caws,Sarah J. Dunstan,Phan Vuong Khac Thai,Beatriz López,Viviana Ritacco,Andrew Kitchen,Tyler S. Brown,Dick van Soolingen,Mary B. O’Neill,Kathryn E. Holt,Kathryn E. Holt,Edward J. Feil,Barun Mathema,Francois Balloux,Vegard Eldholm +31 more
TL;DR: An intimate temporal relationship between European colonial expansion into Africa and the Americas and the spread of L4 tuberculosis (TB) is demonstrated, which suggests that containment efforts at the level of individual countries could be successful.
Journal ArticleDOI
Diversity of Mycobacterium tuberculosis across Evolutionary Scales
TL;DR: In examining genomic data from M.tb samples within and between hosts with TB, it is found that genes involved in the regulation, synthesis, and transportation of immunomodulatory cell envelope lipids appear repeatedly in the extremes of various statistical measures of diversity.
Journal ArticleDOI
Lineage specific histories of Mycobacterium tuberculosis dispersal in Africa and Eurasia.
Mary B. O’Neill,Abigail C. Shockey,Alex Zarley,William Aylward,Vegard Eldholm,Andrew Kitchen,Caitlin S. Pepperell +6 more
TL;DR: The results further reveal that M.tb populations have grown through range expansion, as well as in situ, and delineate the independent evolutionary trajectories of bacterial subpopulations underlying the current pandemic.
Posted ContentDOI
Lineage specific histories of Mycobacterium tuberculosis dispersal in Africa and Eurasia
Mary B. O’Neill,Abigail C. Shockey,Alex Zarley,William Aylward,Vegard Eldholm,Andrew Kitchen,Caitlin S. Pepperell +6 more
TL;DR: The results reveal complex relationships between spatial dispersal and expansion of M.tb populations, and delineate the independent evolutionary trajectories of bacterial sub-populations underlying the current pandemic.