M
Mary E. Rinella
Researcher at Northwestern University
Publications - 153
Citations - 17518
Mary E. Rinella is an academic researcher from Northwestern University. The author has contributed to research in topics: Nonalcoholic fatty liver disease & Steatohepatitis. The author has an hindex of 40, co-authored 125 publications receiving 10593 citations. Previous affiliations of Mary E. Rinella include Agricultural Research Service & Harvard University.
Papers
More filters
Journal ArticleDOI
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases.
Naga Chalasani,Zobair M. Younossi,Joel E. Lavine,Michael Charlton,Kenneth Cusi,Mary E. Rinella,Stephen A. Harrison,Elizabeth M. Brunt,Arun J. Sanyal +8 more
TL;DR: This guidance provides a data-supported approach to the diagnostic, therapeutic, and preventive aspects of NAFLD care.
Journal ArticleDOI
Mechanisms of NAFLD development and therapeutic strategies
TL;DR: Understanding of pathogenic mechanisms and clinical features of NAFLD is driving progress in therapeutic strategies now in clinical trials and the emerging targets for drug development that involve either single agents or combination therapies intended to arrest or reverse disease progression are discussed.
Journal ArticleDOI
Nonalcoholic Fatty Liver Disease: A Systematic Review
TL;DR: How to identify patients with nonalcoholic fatty liver disease at greatest risk of non Alcoholic steatohepatitis and cirrhosis is illustrated and the role and limitations of current diagnostics and liver biopsy are discussed to provide an outline for the management of patients across the spectrum of non alcoholic fatty Liver disease.
Journal ArticleDOI
Non-alcoholic fatty liver disease
TL;DR: In this paper, a global prevalence of 25% and is a leading cause of cirrhosis and hepatocellular carcinoma, and the leading causes of death in people with NAFLD are cardiovascular disease and extrahepatic malignancy.
Journal ArticleDOI
Nonalcoholic fatty liver disease
Elizabeth M. Brunt,Vincent Wai-Sun Wong,Valerio Nobili,Christopher P. Day,Silvia Cristina Sookoian,Jacquelyn J. Maher,Elisabetta Bugianesi,Claude B. Sirlin,Brent A. Neuschwander-Tetri,Mary E. Rinella +9 more
TL;DR: No effective medical interventions exist that completely reverse the disease other than lifestyle changes, dietary alterations and, possibly, bariatric surgery, however, several strategies that target pathophysiological processes such as an oversupply of fatty acids to the liver, cell injury and inflammation are currently under investigation.