M
Maryline Panis
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 27
Citations - 9765
Maryline Panis is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Viral replication & Virus. The author has an hindex of 14, co-authored 23 publications receiving 7887 citations. Previous affiliations of Maryline Panis include Rockefeller University.
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Journal ArticleDOI
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
Daniel Blanco-Melo,Benjamin E. Nilsson-Payant,Wen-Chun Liu,Skyler Uhl,Daisy A. Hoagland,Rasmus Møller,Tristan X. Jordan,Kohei Oishi,Maryline Panis,David H. Sachs,Taia T. Wang,Robert E. Schwartz,Jean K. Lim,Randy A. Albrecht,Benjamin R. tenOever +14 more
TL;DR: It is proposed that reduced innate antiviral defenses coupled with exuberant inflammatory cytokine production are the defining and driving features of COVID-19.
Journal ArticleDOI
A diverse range of gene products are effectors of the type I interferon antiviral response
John W. Schoggins,Sam J. Wilson,Maryline Panis,Mary Murphy,Christopher T. Jones,Paul D. Bieniasz,Charles M. Rice +6 more
TL;DR: It is shown that different viruses are targeted by unique sets of ISGs, and that each viral species is susceptible to multiple antiviral genes, which together encompass a range of inhibitory activities.
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Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry.
Matthew J. Evans,Thomas von Hahn,Donna M. Tscherne,Andrew J. Syder,Maryline Panis,Benno Wölk,Theodora Hatziioannou,Jane A. McKeating,Jane A. McKeating,Paul D. Bieniasz,Charles M. Rice +10 more
TL;DR: Using an iterative expression cloning approach, claudin-1 (CLDN1), a tight junction component that is highly expressed in the liver, is identified as essential for HCV entry and a new target for antiviral drug development.
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Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
Alexander Ploss,Matthew J. Evans,Matthew J. Evans,V. Gaysinskaya,Maryline Panis,Hana You,Ype P. de Jong,Ype P. de Jong,Charles M. Rice +8 more
TL;DR: It is shown that human occludin (OCLN) is an essential HCV cell entry factor that is able to render murine cells infectable with HCVpp and the identification of OCLN as a new HCV entry factor further highlights the importance of the tight junction complex in the viral entry process.
Journal ArticleDOI
Corrigendum: A diverse range of gene products are effectors of the type I interferon antiviral response.
John W. Schoggins,Sam J. Wilson,Maryline Panis,Mary Murphy,Christopher T. Jones,Paul D. Bieniasz,Charles M. Rice +6 more
TL;DR: In this paper, the authors used the WNV-GFP stock used in the data set (Fig. 2 and Supplementary Table 8 of the original Letter) for West Nile virus (WNV) in this Letter was actually Venezuelan equine encephalitis virus (VEEV)-GFP.