M
Masakazu Toi
Researcher at Kyoto University
Publications - 658
Citations - 28522
Masakazu Toi is an academic researcher from Kyoto University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 69, co-authored 578 publications receiving 23200 citations. Previous affiliations of Masakazu Toi include The Breast Cancer Research Foundation & Tokyo Metropolitan Komagome Hospital.
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Safety of trastuzumab in HER2-positive primary breast cancer in Japan: Initial safety report for the large-scale cohort study (JBCRG C-01).
Naohito Yamamoto,Hiroyasu Yamashiro,Hiroji Iwata,Norikazu Masuda,Shoichiro Ohtani,Masato Takahashi,Kosuke Yamazaki,Makoto Kato,Shinji Ohno,Katsumasa Kuroi,Kazuhiko Yamagami,Takashi Morimoto,Yoshie Hasegawa,Toshimi Takano,Takayuki Kadoya,Mitsuchika Hosoda,Hajime Abe,Satoshi Morita,Shinji Yasuno,Masakazu Toi +19 more
TL;DR: The safety of H adjuvant (adj) therapy in an observational study in Japan focused on cardiotoxicity, is evaluated in patients with HER2 positive early breast cancer.
Journal Article
The global cancer genomics consortium's symposium: new era of molecular medicine and epigenetic cancer medicine - cross section of genomics and epigenetics
Masakazu Toi,M. Radhakrishna Pillai,Sudeep Gupta,Rajendra A. Badwe,Maria Carmo-Fonseca,Luís Costa,Loius W.C. Chow,Stefan Knapp,Rakesh Kumar +8 more
TL;DR: The fourth GCGC Symposium focused on a cross section of genomic and epigenetic cancer medicine: Cross Section of Genomics and Epigenetics, which focused on cancer stem cells and self-renewal, cancer transcriptome, tumor heterogeneity, tumor biology, breast cancer genomics, targeted therapeutics and personalized medicine.
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Adjuvant olaparib in the subset of patients from Japan with BRCA1- or BRCA2-mutated high-risk early breast cancer from the phase 3 OlympiA trial
Hideko Yamauchi,Masakazu Toi,Shinichi Takayama,Seigo Nakamura,Toshimi Takano,Karen Y. Cui,Christine M. Pierce Campbell,Charles E. Geyer,Andrew Tutt +8 more
TL;DR: The efficacy and safety of olaparib compared with placebo in the subset of patients from Japan in the phase 3 OlympiA trial (NCT02032823) are reported here and contextualized with reference to the global population as mentioned in this paper .
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Autophagy is a mechanism of resistance to anticancer drugs that can be targeted to improve the effectiveness of cancer therapy
TL;DR: OOTR membership offers many benefits, among which a greatly discounted attendance fee to international congresses as well as the opportunity to apply for grants to attend educational seminars and study programs.
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Murine breast cancers disorganize the liver transcriptome in a zonated manner
Alexis Vandenbon,Rin Mizuno,Riyo Konishi,Masaya Onishi,Kyoko Masuda,Yuka Kobayashi,T. Kawamoto,Ayako Suzuki,Chenfeng He,Yuki Nakamura,Kosuke Kawaguchi,Masakazu Toi,Masahito Shimizu,Yasuhito Tanaka,Yutaka Suzuki,Shinpei Kawaoka +15 more
TL;DR: In this paper , the abundance and zonation of hepatic genes in cancer-bearing mice were investigated using spatial transcriptomics, and it was shown that breast cancers disorganize hepatic transcriptomes in various distinct manners depending on biological pathways.