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Masakazu Toi

Researcher at Kyoto University

Publications -  658
Citations -  28522

Masakazu Toi is an academic researcher from Kyoto University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 69, co-authored 578 publications receiving 23200 citations. Previous affiliations of Masakazu Toi include The Breast Cancer Research Foundation & Tokyo Metropolitan Komagome Hospital.

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Increase in the circulating level of hepatocyte growth factor in gastric cancer patients.

TL;DR: The circulating levels of HGF were elevated in approximately one-third of patients with primary gastric cancer, particularly in those with high grades of histological tumour invasion and venous invasion, and frequently in patients with distant metastases, suggesting that HGF might play important roles in the tumour progression of gastriccancer.
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Relationship between matrix metalloproteinase expression and tumor angiogenesis in human breast carcinoma

TL;DR: MMP-2 and MMP-9 expressions were frequently co-upregulated with endothelial growth regulators in human breast cancer tissues, which underlines the cooperative function of MMPs in neovascularization.
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Economic evaluation of the 21-gene signature (Oncotype DX) in lymph node-negative/positive, hormone receptor-positive early-stage breast cancer based on Japanese validation study (JBCRG-TR03).

TL;DR: The inclusion of the 21-gene signature in Japan’s social health insurance benefit package for not only LN− diseases but also LN+ diseases is cost-effective and can be justifiable as an efficient use of finite resources for health care.
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Insights Into Breast Cancer in the East vs the West: A Review

TL;DR: The inclusion of more women from Asia in clinical trials and epidemiologic and translational studies may help unravel the interethnic heterogeneity of BCs and elucidate the complex interplay between environmental and intrinsic factors in its pathogenesis.