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Masakazu Toi

Researcher at Kyoto University

Publications -  658
Citations -  28522

Masakazu Toi is an academic researcher from Kyoto University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 69, co-authored 578 publications receiving 23200 citations. Previous affiliations of Masakazu Toi include The Breast Cancer Research Foundation & Tokyo Metropolitan Komagome Hospital.

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Occurrence of senescence-escaping cells in doxorubicin-induced senescence is enhanced by PD0332991, a cyclin-dependent kinase 4/6 inhibitor, in colon cancer HCT116 cells.

TL;DR: The present study investigated the relevance of the cell cycle phase and colony formation in the DOX-induced senescence of human colon cancer HCT116 cells and co-treatment of PD0332991 with DOX slowed progression of cells in the G1 phase resulting in enhanced colony formation.
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Neoadjuvant exemestane for 24 weeks in postmenopausal women with hormone receptor positive stage II or IIIA breast cancer (JFMC34–0601)

TL;DR: Exemestane has shown attractive response for hormone receptor positive breast cancer in neoadjuvant setting with sufficient safety and tolerability, and central pathological review exhibited that biomarker changes during the treatment correlated with tumor response.
Journal Article

[5'-deoxy-5-fluorouridine (5'-DFUR), mitomycin C (MMC), etoposide and medroxy progesterone acetate (MPA) in a previously treated patient with advanced breast cancer].

TL;DR: An advanced breast cancer patient refractory to CAF, 5-FU-Methotrexate sequential therapy and Tamoxifen was treated with the combination 5' DFUR, MMC, Etoposide and MPA, and it is suggested that the combination therapy may be useful for previously treated patients withAdvanced breast cancer.