M
Maurice Charlet
Researcher at Centre national de la recherche scientifique
Publications - 21
Citations - 1662
Maurice Charlet is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Ecdysone & Ecdysteroid. The author has an hindex of 13, co-authored 21 publications receiving 1575 citations. Previous affiliations of Maurice Charlet include University of Wisconsin-Madison.
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Journal ArticleDOI
Innate Immunity: ISOLATION OF SEVERAL CYSTEINE-RICH ANTIMICROBIAL PEPTIDES FROM THE BLOOD OF A MOLLUSC, MYTILUS EDULIS
Maurice Charlet,Serguey Chernysh,Hervé Philippe,Charles Hetru,Jules A. Hoffmann,Philippe Bulet +5 more
TL;DR: It is argued that circulating antimicrobial peptides represent an ancient host defense mechanism that predated the separation between molluscs and arthropods at the root of the Cambrian, about 545 million years ago.
Journal ArticleDOI
A novel inducible antibacterial peptide of Drosophila carries an O-glycosylated substitution.
Philippe Bulet,Jean-Luc Dimarcq,Charles Hetru,Marie Lagueux,Maurice Charlet,G. Hegy,A. Van Dorsselaer,Jules A. Hoffmann +7 more
TL;DR: The isolation of a novel 19-residue proline-rich inducible antibacterial peptide from Drosophila carries a substitution as evidenced by molecular mass determinations; this substitution represents a post-translational modification essential for the full biological activity of this novel peptide.
Journal ArticleDOI
Cloning and analysis of a cecropin gene from the malaria vector mosquito, Anopheles gambiae.
Jacopo Vizioli,Philippe Bulet,Maurice Charlet,Carl Lowenberger,Claudia Blass,H M Müller,George Dimopoulos,Jules A. Hoffmann,Fotis C. Kafatos,Adam M. Richman +9 more
TL;DR: The isolation of cDNA and genomic clones encoding a cecropin antibacterial peptide from the malaria vector mosquito Anopheles gambiae was described and the locus was mapped to polytene division 1C of the X chromosome.
Journal ArticleDOI
Insect immunity : isolation of three novel inducible antibacterial defensins from the vector mosquito, Aedes aegypti
Carl Lowenberger,Philippe Bulet,Maurice Charlet,Charles Hetru,Bradley A. Hodgeman,Bruce M. Christensen,Jules A. Hoffmann +6 more
TL;DR: The amino acid sequences clearly show that the three peptides are novel isoforms of the insect defensin family of antibacterial peptides, which are potently active against Gram-positive bacteria and against one of the Gram-negative bacteria that were tested.
Journal ArticleDOI
Antimicrobial activity spectrum, cDNA cloning, and mRNA expression of a newly isolated member of the cecropin family from the mosquito vector Aedes aegypti.
Carl Lowenberger,Maurice Charlet,Jacopo Vizioli,Sofie Kamal,Adam M. Richman,Bruce M. Christensen,Philippe Bulet +6 more
TL;DR: An antimicrobial peptide belonging to the cecropin family was isolated from the hemolymph of bacteria-challenged adult Aedes aegypti, which is devoid of a tryptophan residue and C-terminal amidation and shows a lower activity for the mosquito molecule.