B
Bruce M. Christensen
Researcher at University of Wisconsin-Madison
Publications - 172
Citations - 8915
Bruce M. Christensen is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Aedes aegypti & Brugia malayi. The author has an hindex of 50, co-authored 171 publications receiving 8299 citations. Previous affiliations of Bruce M. Christensen include Murray State University.
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Journal ArticleDOI
Evolutionary Dynamics of Immune-Related Genes and Pathways in Disease-Vector Mosquitoes
Robert M. Waterhouse,Evgenia V. Kriventseva,Stephan Meister,Zhiyong Xi,Kanwal S. Alvarez,Lyric C. Bartholomay,Carolina Barillas-Mury,Guowu Bian,Stéphanie Blandin,Bruce M. Christensen,Yuemei Dong,Haobo Jiang,Michael R. Kanost,Anastasios C. Koutsos,Elena A. Levashina,Jianyong Li,Petros Ligoxygakis,Robert M. MacCallum,George F. Mayhew,António M. Mendes,Kristin Michel,Mike A. Osta,Susan M. Paskewitz,Sang Woon Shin,Dina Vlachou,Lihui Wang,Weiqi Wei,Liangbiao Zheng,Zhen Zou,David W. Severson,Alexander S. Raikhel,Fotis C. Kafatos,George Dimopoulos,Evgeny M. Zdobnov,George K. Christophides +34 more
TL;DR: Analysis of immune signaling pathways and response modules reveals both conservative and rapidly evolving features associated with different functional gene categories and particular aspects of immune reactions, suggesting how innate immunity may have evolved.
Journal ArticleDOI
Melanogenesis and associated cytotoxic reactions: applications to insect innate immunity.
TL;DR: This review examines some of the factors that influence enzyme-mediated melanogenic responses, and how these responses likely contribute to blood cell-mediated, target-specific cytotoxicity in immune challenged insects.
Journal ArticleDOI
Sequencing of Culex quinquefasciatus Establishes a Platform for Mosquito Comparative Genomics
Peter Arensburger,Karyn Megy,Robert M. Waterhouse,Robert M. Waterhouse,Jenica L. Abrudan,Paolo Amedeo,Beatriz García Antelo,Lyric C. Bartholomay,Shelby L. Bidwell,Elisabet Caler,Francisco Camara,Corey L. Campbell,Kathryn S. Campbell,Claudio Casola,Marta T Castro,Ishwar Chandramouliswaran,Sinéad B. Chapman,Scott Christley,Javier Costas,Eric Eisenstadt,Cédric Feschotte,Claire M. Fraser-Liggett,Roderic Guigó,Brian J. Haas,Martin Hammond,Bill S. Hansson,Janet Hemingway,Sharon R. Hill,Clint Howarth,Rickard Ignell,Ryan C. Kennedy,Chinnappa D. Kodira,Neil F. Lobo,Chunhong Mao,George F. Mayhew,Kristin Michel,Akio Mori,Nannan Liu,Horacio Naveira,Vishvanath Nene,Vishvanath Nene,Nam P. Nguyen,Matthew D. Pearson,Ellen J. Pritham,Daniela Puiu,Yumin Qi,Hilary Ranson,José M. C. Ribeiro,Hugh M Roberston,David W. Severson,Martin Shumway,Mario Stanke,Robert L. Strausberg,Cheng Sun,Granger G. Sutton,Zhijian Jake Tu,Jose M. C. Tubio,Maria F. Unger,Dana L. Vanlandingham,Albert J. Vilella,Owen White,Jared White,Charles S. Wondji,Jennifer R. Wortman,Evgeny M. Zdobnov,Evgeny M. Zdobnov,Evgeny M. Zdobnov,Bruce W. Birren,Bruce M. Christensen,Frank H. Collins,Anthony J. Cornel,George Dimopoulos,Linda Hannick,Stephen Higgs,Gregory C. Lanzaro,Daniel Lawson,Norman H. Lee,Marc A. T. Muskavitch,Marc A. T. Muskavitch,Marc A. T. Muskavitch,Alexander S. Raikhel,Peter W. Atkinson +81 more
TL;DR: The genomic sequence of C. quinquefasciatus is described, which reveals distinctions related to vector capacities and habitat preferences, and confirmed that inoculation with unfamiliar bacteria prompted strong immune responses in Culex.
Journal ArticleDOI
Genetics of Mosquito Vector Competence
TL;DR: With the recent successes in the field of mosquito germ line transformation, it seems likely that the generation of a pathogen-resistant mosquito population from a susceptible population soon will become a reality.
Journal ArticleDOI
Melanization immune responses in mosquito vectors
TL;DR: In this article, the authors summarize knowledge about melanin biosynthesis in diverse physiological processes and the gaps in knowledge that must be addressed if this immune process is to be manipulated in genetic-based control strategies.