M
Maxim Pimkin
Researcher at Fox Chase Cancer Center
Publications - 23
Citations - 1089
Maxim Pimkin is an academic researcher from Fox Chase Cancer Center. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 11, co-authored 15 publications receiving 987 citations. Previous affiliations of Maxim Pimkin include Children's Hospital of Philadelphia & University of Pennsylvania.
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Journal ArticleDOI
Prevalence and molecular epidemiology of CTX-M extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Russian hospitals
TL;DR: This study provides further evidence of the global dissemination of CTX-M type ESBLs and emphasizes the need for their epidemiological monitoring.
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Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development.
Vikram R Paralkar,Tejaswini Mishra,Jing Luan,Yu Yao,Andrew V. Kossenkov,Stacie M. Anderson,Margaret C. Dunagin,Maxim Pimkin,Meghneel Gore,Diana Sun,Neeraja Konuthula,Arjun Raj,Xiuli An,Narla Mohandas,David M. Bodine,Ross C. Hardison,Mitchell J. Weiss +16 more
TL;DR: RNA interference assays of 21 abundant erythroid-specific murine lncRNAs in primary mouse erystroid precursors identified 7 whose knockdown inhibited terminal erythyroid maturation, suggesting that lack of conservation between mammalian species does not predict lack of function.
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Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration.
Weisheng Wu,Yong Cheng,Cheryl A. Keller,Jason Ernst,Jason Ernst,Swathi Ashok Kumar,Tejaswini Mishra,Christapher S. Morrissey,Christine M. Dorman,Kuan-Bei Chen,Daniela I. Drautz,Belinda Giardine,Yoichiro Shibata,Lingyun Song,Maxim Pimkin,Gregory E. Crawford,Terrence S. Furey,Manolis Kellis,Manolis Kellis,Webb Miller,James Taylor,Stephan C. Schuster,Yu Zhang,Francesca Chiaromonte,Gerd A. Blobel,Mitchell J. Weiss,Ross C. Hardison +26 more
TL;DR: The results indicate that during erythroid differentiation, the broad features of chromatin states are established at the stage of lineage commitment, largely independently of GATA1, which determine permissiveness for expression, with subsequent induction or repression mediated by distinctive combinations of transcription factors.
Journal ArticleDOI
Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis
Maxim Pimkin,Andrew V. Kossenkov,Tejaswini Mishra,Christapher S. Morrissey,Weisheng Wu,Cheryl A. Keller,Gerd A. Blobel,Dongwon Lee,Michael A. Beer,Ross C. Hardison,Mitchell J. Weiss +10 more
TL;DR: These findings reveal important new insights into how ERY and MEG lineages arise from a common bipotential progenitor via overlapping and divergent functions of shared hematopoietic transcription factors.
Journal ArticleDOI
Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis
Weisheng Wu,Christapher S. Morrissey,Cheryl A. Keller,Tejaswini Mishra,Maxim Pimkin,Gerd A. Blobel,Mitchell J. Weiss,Ross C. Hardison +7 more
TL;DR: It is found that sites of occupancy shift dramatically during commitment to the erythroid lineage, vary further during terminal maturation, and are strongly associated with changes in gene expression.