M
Megan E. Drew
Researcher at University College London
Publications - 5
Citations - 619
Megan E. Drew is an academic researcher from University College London. The author has contributed to research in topics: Ghrelin & Peptide YY. The author has an hindex of 4, co-authored 5 publications receiving 545 citations.
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Journal ArticleDOI
A link between FTO, ghrelin, and impaired brain food-cue responsivity
Efthimia Karra,Owen O'Daly,Agharul I. Choudhury,Ahmed Yousseif,Steven Millership,Marianne T. Neary,William R. Scott,Keval Chandarana,Sean Manning,Martin E. Hess,Hiroshi Iwakura,Takashi Akamizu,Queensta Millet,Cigdem Gelegen,Megan E. Drew,Sofia Rahman,Julian J. Emmanuel,Steven Williams,Ulrich Rüther,Jens C. Brüning,Dominic J. Withers,Fernando Zelaya,Rachel L. Batterham +22 more
TL;DR: Functional MRI in normal-weight AA and TT humans found that the FTO genotype modulates the neural responses to food images in homeostatic and brain reward regions, and shows that FTO regulates ghrelin, a key mediator of ingestive behavior.
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Diet and Gastrointestinal Bypass-Induced Weight Loss The Roles of Ghrelin and Peptide YY
Keval Chandarana,Cigdem Gelegen,Efthimia Karra,Agharul I. Choudhury,Megan E. Drew,Véronique Fauveau,Benoit Viollet,Fabrizio Andreelli,Dominic J. Withers,Rachel L. Batterham +9 more
TL;DR: PYY plays a key role in mediating the early weight loss observed post-GIBP, whereas relative PYY deficiency during dieting may compromise weight-loss attempts.
Journal ArticleDOI
Subject standardization, acclimatization, and sample processing affect gut hormone levels and appetite in humans.
Keval Chandarana,Megan E. Drew,Julian J. Emmanuel,Efthimia Karra,Cigdem Gelegen,Philip Chan,Nicholas J. Cron,Rachel L. Batterham +7 more
TL;DR: Accurate assessment of appetite, feeding behavior, and gut hormone concentrations requires standardization of prior food consumption and subject acclimatization to the study protocol.
Journal ArticleDOI
Metabolic State Alters Economic Decision Making under Risk in Humans
TL;DR: It is shown that human risk preferences are exquisitely sensitive to current metabolic state, in a direction consistent with ecological models of feeding behaviour but not predicted by normative economic theory, and has significant implications for both real-world economic transactions and for aberrant decision-making in eating disorders and obesity.