M
Megumi Hatori
Researcher at Salk Institute for Biological Studies
Publications - 27
Citations - 4291
Megumi Hatori is an academic researcher from Salk Institute for Biological Studies. The author has contributed to research in topics: Circadian rhythm & Circadian clock. The author has an hindex of 17, co-authored 26 publications receiving 3497 citations. Previous affiliations of Megumi Hatori include National Presto Industries & Keio University.
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Journal ArticleDOI
Histone Lysine Demethylase JARID1a Activates CLOCK-BMAL1 and Influences the Circadian Clock
Luciano DiTacchio,Hiep D. Le,Christopher Vollmers,Megumi Hatori,Michael Witcher,Julie Secombe,Satchidananda Panda +6 more
TL;DR: Depletion of JARID1a in mammalian cells reduced Per promoter histone acetylation, dampened expression of canonical circadian genes, and shortened the period of circadian rhythms, indicating a nonredundant role in circadian oscillator function.
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The emerging roles of melanopsin in behavioral adaptation to light
TL;DR: Recent advances in understanding of the emerging roles of melanopsin and ipRGCs offer new avenues to understand the role of ambient light in sleep, alertness, dependent physiologies and potential pharmacological intervention as well as lifestyle modifications to improve the quality of life.
Journal ArticleDOI
Global rise of potential health hazards caused by blue light-induced circadian disruption in modern aging societies
Megumi Hatori,Megumi Hatori,Claude Gronfier,Russell N. Van Gelder,Paul S. Bernstein,Josep Carreras,Satchidananda Panda,Frederick Marks,David H. Sliney,Charles E. Hunt,Tsuyoshi Hirota,Toshiharu Furukawa,Kazuo Tsubota +12 more
TL;DR: The importance of being exposed to light at optimal times and intensities during the day, based on the concept of the circadian clock, is claimed to improve quality of life to have a healthy and longer life.
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Violet Light Exposure Can Be a Preventive Strategy Against Myopia Progression
Hidemasa Torii,Toshihide Kurihara,Yuko Seko,Kazuno Negishi,Kazuhiko Ohnuma,Takaaki Inaba,Takaaki Inaba,Motoko Kawashima,Xiaoyan Jiang,Shinichiro Kondo,Maki Miyauchi,Yukihiro Miwa,Yusaku Katada,Kiwako Mori,Keiichi Kato,Kinya Tsubota,Kinya Tsubota,Hiroshi Goto,Mayumi Oda,Megumi Hatori,Megumi Hatori,Kazuo Tsubota +21 more
TL;DR: It is shown that violet light (VL, 360–400 nm wavelength) suppresses myopia progression and is one of the important outdoor environmental factors for myopia control.
Journal ArticleDOI
Small-molecule antagonists of melanopsin-mediated phototransduction
Kenneth A. Jones,Megumi Hatori,Ludovic S. Mure,Jayne R. Bramley,Roman Artymyshyn,Sang Phyo Hong,Mohammad R. Marzabadi,Huailing Zhong,Jeffrey Sprouse,Quansheng Zhu,Andrew T. E. Hartwick,Patricia J. Sollars,Gary E. Pickard,Satchidananda Panda +13 more
TL;DR: The identification of a potent synthetic melanopsin antagonist with in vivo activity is described and the discovery of opsinamides raises the prospect of therapeutic control of the melanopsIn phototransduction system to regulate light-dependent behavior and remediate pathological conditions.