Mei-Ling Ting Lee

TL;DR: This study is the first to identify and define miRNA expression in circulating plasma microvesicles of normal subjects, and provides a basis for future studies to determine the predictive role of peripheral blood miRNA signatures in human disease.

TL;DR: In this article, a controlled experiment was conducted to investigate inherent variability in gene expression data and the extent to which replication in an experiment produces more consistent and reliable findings by introducing a statistical model to describe the probability that mRNA is contained in the target sample tissue, converted to probe, and ultimately detected on the slide.

TL;DR: Deviation from recommended timing of doses appears to be greater than from prescribed number of doses, and pharmacy dispensing records demonstrate predictive validity as measures of cumulative exposure and gaps in medication supply.

TL;DR: The results identify regulatory DRD2 polymorphisms that modify mRNA expression and splicing and working memory pathways that are associated with greater activity of striatum and prefrontal cortex measured with fMRI and with reduced performance in working memory and attentional control tasks in healthy humans.

TL;DR: The Wilcoxon signed rank test is a frequently used nonparametric test for paired data based on independent units of analysis that is able to incorporate clustering and is shown to be asymptotically normal as the number of clusters becomes large, if the cluster size is bounded.