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Clay B. Marsh
Researcher at West Virginia University
Publications - 213
Citations - 13969
Clay B. Marsh is an academic researcher from West Virginia University. The author has contributed to research in topics: Monocyte & Receptor. The author has an hindex of 59, co-authored 213 publications receiving 12913 citations. Previous affiliations of Clay B. Marsh include Institute for Systems Biology & Ohio State University.
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Journal ArticleDOI
Detection of microRNA Expression in Human Peripheral Blood Microvesicles
Melissa Piper Hunter,Noura Ismail,Noura Ismail,Xiaoli Zhang,Baltazar D. Aguda,Eun Joo Lee,Lianbo Yu,Tao Xiao,Jeffrey Schafer,Mei-Ling Ting Lee,Thomas D. Schmittgen,S. Patrick Nana-Sinkam,David Jarjoura,Clay B. Marsh,Clay B. Marsh +14 more
TL;DR: This study is the first to identify and define miRNA expression in circulating plasma microvesicles of normal subjects, and provides a basis for future studies to determine the predictive role of peripheral blood miRNA signatures in human disease.
Journal ArticleDOI
Acquired Weakness, Handgrip Strength, and Mortality in Critically Ill Patients
Naeem A. Ali,James M. O'Brien,Stephen Hoffmann,Gary Phillips,Allan Garland,James C. W. Finley,Khalid F. Almoosa,Rana Hejal,Karen M. Wolf,Stanley Lemeshow,Alfred F. Connors,Clay B. Marsh +11 more
TL;DR: Handgrip strength was lower in subjects with ICUAP and had good test performance for diagnosingICUAP, and handgrip dynamometry is also independently associated with poor hospital outcome and may serve as a simple test to identify ICU AP.
Journal ArticleDOI
Implementing genomic medicine in the clinic: the future is here
Teri A. Manolio,Rex L. Chisholm,Brad Ozenberger,Dan M. Roden,Marc S. Williams,Richard Trevor Wilson,David P. Bick,Erwin P. Bottinger,Murray H. Brilliant,Charis Eng,Kelly A. Frazer,Bruce R. Korf,David H. Ledbetter,James R. Lupski,Clay B. Marsh,David A. Mrazek,Michael F. Murray,Peter H. O'Donnell,Daniel J. Rader,Mary V. Relling,Alan R. Shuldiner,David Valle,Richard M. Weinshilboum,Eric D. Green,Geoffrey S. Ginsburg +24 more
TL;DR: The National Human Genome Research Institute brought together a number of institutions to describe their ongoing projects and challenges, identify common infrastructure and research needs, and outline an implementation framework for investigating and introducing similar programs elsewhere.
Journal ArticleDOI
Macrophage microvesicles induce macrophage differentiation and miR-223 transfer.
Noura Ismail,Yijie Wang,Duaa Dakhlallah,Leni Moldovan,Kitty Agarwal,Kara Batte,Prexy Shah,Jon Wisler,Timothy D. Eubank,Susheela Tridandapani,Michael E. Paulaitis,Melissa G. Piper,Clay B. Marsh +12 more
TL;DR: Macrophage-derived microvesicles are characterized and their role in the differentiation of naive monocytes is explored and the miRNA content is identified, finding that RNA molecules contained in the macrophages were transported to target cells, including mono cytes, endothelial cells, epithelial Cells, and fibroblasts.
Journal ArticleDOI
Glucose variability and mortality in patients with sepsis.
Naeem A. Ali,James M. O'Brien,Kathleen Dungan,Gary Phillips,Clay B. Marsh,Stanley Lemeshow,Alfred F. Connors,Jean-Charles Preiser +7 more
TL;DR: Glucose variability is independently associated with hospital mortality in sepsis and strategies to reduce glucose variability should be studied to determine whether they improve the outcomes of septic patients.