Melina Fan

TL;DR: A pipeline for the rapid design, assembly, and validation of cell-free, paper-based sensors for the detection of the Zika virus RNA genome is reported, which detect clinically relevant concentrations of Zika virus sequences and demonstrate specificity against closely related Dengue virus sequences.

TL;DR: Addgene provides an open forum for plasmid sharing and complements model organism–specific resources and reagent collections, such as those distributed by the American Type Culture Collection and the Developmental Hybridoma Bank.

TL;DR: This review covers the basics ofCRISPR/Cas9, describes several publicly available CRISPR libraries, and provides a general protocol for conducting genome‐wide screening experiments using CRISpr/Cas 9.

TL;DR: In this article , an optimized viral toolkit (VTK) is presented for efficient combinatorial targeting of cell types by integrating structural improvements of AAV vectors with innovative molecular tools.

TL;DR: Addgene, a nonprofit organization, is creating a central plasmid repository where scientists can search for and request plasmids online and relieve investigators of the time and effort needed to answer requests, as well as provide a reliable archival service forplasmids and maps.