M
Melissa Behr
Researcher at University of Wisconsin-Madison
Publications - 34
Citations - 3604
Melissa Behr is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Pseudogymnoascus destructans & Toxicity. The author has an hindex of 27, co-authored 34 publications receiving 3302 citations. Previous affiliations of Melissa Behr include New York State Department of Health & Behr.
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Journal ArticleDOI
Bat White-Nose Syndrome: An Emerging Fungal Pathogen?
David S. Blehert,Alan C. Hicks,Melissa Behr,Carol U. Meteyer,Brenda M. Berlowski-Zier,Elizabeth L. Buckles,Jeremy T. H. Coleman,Scott R. Darling,Andrea Gargas,Robyn Niver,Joseph C. Okoniewski,Robert J. Rudd,Ward B. Stone +12 more
TL;DR: Direct microscopy and culture analyses demonstrated that the skin of WNS-affected bats is colonized by a psychro-philic fungus that is phylogenetically related to Geomyces spp.
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Experimental infection of bats with Geomyces destructans causes white-nose syndrome
Jeffrey M. Lorch,Carol U. Meteyer,Melissa Behr,Justin G. Boyles,Paul M. Cryan,Alan C. Hicks,Anne Ballmann,Jeremy T. H. Coleman,David N. Redell,DeeAnn M. Reeder,David S. Blehert +10 more
TL;DR: It is demonstrated that exposure of healthy little brown bats to pure cultures of G. destructans causes white-nose syndrome and that the recent emergence of WNS in North America may represent translocation of the fungus to a region with a naive population of animals.
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Histopathologic criteria to confirm white-nose syndrome in bats.
Carol U. Meteyer,Elizabeth L. Buckles,David S. Blehert,Alan C. Hicks,D. Earl Green,Valerie I. Shearn-Bochsler,Nancy J. Thomas,Andrea Gargas,Melissa Behr +8 more
TL;DR: White-nose syndrome is a cutaneous fungal disease of hibernating bats associated with a novel Geomyces sp.
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Liver-specific Deletion of the NADPH-Cytochrome P450 Reductase Gene: IMPACT ON PLASMA CHOLESTEROL HOMEOSTASIS AND THE FUNCTION AND REGULATION OF MICROSOMAL CYTOCHROME P450 AND HEME OXYGENASE *
Jun Gu,Yan Weng,Qing Yu Zhang,Huadong Cui,Melissa Behr,Lin Wu,Weizhu Yang,Li Zhang,Xinxin Ding +8 more
TL;DR: The data indicate the absence of significant alternative redox partners for liver microsomal CYP and HO, provide in vivo evidence for the significance of hepatic CPR-dependent enzymes in cholesterol homeostasis and systemic drug clearance, and reveal novel regulatory pathways of CYP expression associated with altered cellularHomeostasis.
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In vivo mechanisms of tissue-selective drug toxicity: effects of liver-specific knockout of the NADPH-cytochrome P450 reductase gene on acetaminophen toxicity in kidney, lung, and nasal mucosa.
Jun Gu,Huadong Cui,Melissa Behr,Li Zhang,Qing Yu Zhang,Weizhu Yang,Jack A. Hinson,Xinxin Ding,Xinxin Ding +8 more
TL;DR: The results indicate that acetaminophen toxicity in the nasal mucosa is not dependent on hepatic microsomal P450-catalyzed metabolic activation and thatacetaminophenoxicity in the lung, kidney, and lateral nasal glands is at least partly caused by liver-derived acetaminphen metabolites.