M
Michael A. Gropper
Researcher at University of California, San Francisco
Publications - 122
Citations - 6762
Michael A. Gropper is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Lung injury & Intensive care. The author has an hindex of 41, co-authored 120 publications receiving 6196 citations. Previous affiliations of Michael A. Gropper include University of California & University of California, Berkeley.
Papers
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Journal ArticleDOI
Transfusion-related acute lung injury: Incidence and risk factors
Pearl Toy,Ognjen Gajic,Peter Bacchetti,Mark R. Looney,Michael A. Gropper,Rolf D. Hubmayr,Clifford A. Lowell,Philip J. Norris,Philip J. Norris,Edward L. Murphy,Edward L. Murphy,Richard B. Weiskopf,Gregory A. Wilson,Monique Koenigsberg,Deanna C. Lee,Randy M. Schuller,Ping Wu,Barbara Grimes,Manish J. Gandhi,Jeffrey L. Winters,David C. Mair,Nora V. Hirschler,Nora V. Hirschler,Rosa Sanchez Rosen,Rosa Sanchez Rosen,Michael A. Matthay +25 more
TL;DR: The identified risk factors provide potential targets for reducing residual TRALI and little or no risk was associated with older red blood cell units, noncognate or weak cognate class II antibody, or class I antibody.
Journal ArticleDOI
Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes
TL;DR: The unexpected membrane colocalization of MIWC and GLIP in several tissues suggests an interaction at the molecular and/or functional levels in the urinary concentrating mechanism, cerebrospinal fluid absorption, ocular fluid balance, fecal dehydration, and airway humidification.
Journal ArticleDOI
Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues
Antonio Frigeri,Michael A. Gropper,Fuminori Umenishi,M. Kawashima,Dennis Brown,Alan S. Verkman +5 more
TL;DR: The tissue-specific expression of MIWC suggests a role in fluid transport and/or cell volume regulation in stomach and glandular epithelia, and orthogonal arrays of particles have been visualized by freeze-fracture electron microscopy, suggesting that MIWC may be the OAP protein.
Journal ArticleDOI
Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury.
Teiji Sawa,Timothy L. Yahr,Maria Ohara,Kiyoyasu Kurahashi,Michael A. Gropper,Jeanine P. Wiener-Kronish,Dara W. Frank +6 more
TL;DR: It is shown that the P. aeruginosa homolog of the Yersinia V antigen, PcrV, is involved in the translocation of type III toxins, which ensured the survival of challenged mice and decreased lung inflammation and injury.
Journal ArticleDOI
Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia
Kiyoyasu Kurahashi,Osamu Kajikawa,Teiji Sawa,Maria Ohara,Michael A. Gropper,Dara W. Frank,Thomas R. Martin,Jeanine P. Wiener-Kronish +7 more
TL;DR: The results demonstrate the importance of compartmentalization of inflammatory mediators in the lung, and the crucial role of bacterial cytotoxins in causing alveolar epithelial damage in the pathogenesis of acute septic shock in P. aeruginosa pneumonia.