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Michael Aviram

Researcher at Technion – Israel Institute of Technology

Publications -  489
Citations -  32705

Michael Aviram is an academic researcher from Technion – Israel Institute of Technology. The author has contributed to research in topics: Cholesterol & Lipoprotein. The author has an hindex of 94, co-authored 479 publications receiving 31141 citations. Previous affiliations of Michael Aviram include University of Tromsø & Steward Health Care System.

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Changes in lipoproteins and subfractions following oophorectomy and oestrogen replacement in peri-menopausal women.

TL;DR: Serum cholesterol concentrations in lipoprotein fractions and subfractions were determined in 11 peri-menopausal women both before and after bilateral oophorectomy, as well as 60 days after commencement of oral oestradiol replacement therapy.
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Increased concentration of high density lipoprotein in plasma and decreased platelet aggregation in primary biliary cirrhosis

TL;DR: The abnormal lipoproteins in these patients may contribute to their abnormal in vitro platelet aggregation, and little correlation between lipoprotein disorders and clinical condition was found.
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Paraoxonase 1 interactions with atherosclerotic lesions and arterial macrophages protect against foam cell formation and atherosclerosis development

TL;DR: It is of interest that, similarly to HDL-associated PON1 antioxidant properties, PON2 possesses similar antioxidant/antiatherogenic characteristics towards arterial macrophage foam cells, the hallmark of early atherogenesis.
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Intralipid infusion in patients with familial hypercholesterolemia. Effect of serum and plasma lipoproteins on platelet aggregation and on macrophage cholesterol metabolism.

TL;DR: It is concluded that intralipid infusion abolishes serum ability to stimulate cholesterol esterification in cultured macrophages, and exhibits inhibitory effects upon platelet aggregation.
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Omapatrilat decreased macrophage oxidative status and atherosclerosis progression in atherosclerotic apolipoprotein E-deficient mice.

TL;DR: Omapatrilat has a substantial anti-atherosclerotic effect, which can be related not only to BP reduction but also to its ability to reduce oxidative stress in atherosclerosis E0 mice.