M
Michael Aviram
Researcher at Technion – Israel Institute of Technology
Publications - 489
Citations - 32705
Michael Aviram is an academic researcher from Technion – Israel Institute of Technology. The author has contributed to research in topics: Cholesterol & Lipoprotein. The author has an hindex of 94, co-authored 479 publications receiving 31141 citations. Previous affiliations of Michael Aviram include University of Tromsø & Steward Health Care System.
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Increased platelet aggregation during alimentary hyperlipemia in normal and hypertriglyceridemic subjects
TL;DR: It is indicated that the intake of fatty meals induces acute disturbance in platelet aggregation, favoring thrombosis, more comprehensive in hyperlipemic patients and after a saturated-fat-rich meal.
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Induction of PPARgamma1 expression in human THP-1 monocytic leukemia cells by 9-cis-retinoic acid is associated with cellular growth suppression.
TL;DR: RA induction of PPARgamma1 may block cell growth and may have application for the treatment of proliferative diseases.
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Platelet-modified low density lipoprotein induces macrophage cholesterol accumulation and platelet activation.
Michael Aviram,Bianca Fuhrman,Shlomo Keidar,Irit Maor,Mira Rosenblat,Gertrude Dankner,Gerald J. Brook +6 more
TL;DR: It is concluded that platelet-modified LDL interacts with the LDL receptor and induces macrophage cholesterol accumulation and could be considered to be pro-atherogenic.
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Paraoxonase 1 protects macrophages from atherogenicity of a specific triglyceride isolated from human carotid lesion
Hagai Tavori,Michael Aviram,Soliman Khatib,Ramadan Musa,Dalit Mannheim,Ron Karmeli,Jacob Vaya +6 more
TL;DR: It is concluded that macrophage ROS production by LLE occurs in the presence of a specific triglyceride and requires mitochondrial involvement, and Lipid peroxide in the triglyceride can also facilitate lipid autoxidation.
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Impact of heme oxygenase-1 on cholesterol synthesis, cholesterol efflux and oxysterol formation in cultured astroglia.
Jacob R. Hascalovici,Wei Song,Jacob Vaya,Soliman Khatib,Bianca Fuhrman,Michael Aviram,Hyman M. Schipper,Hyman M. Schipper +7 more
TL;DR: The effects of HO‐1 over‐expression and its byproducts iron, CO, carbon monoxide and bilirubin on CH biosynthesis, CH efflux and oxysterol formation in cultured astroglia was determined.