M
Michael F. Salamone
Researcher at Ontario Ministry of the Environment
Publications - 12
Citations - 1647
Michael F. Salamone is an academic researcher from Ontario Ministry of the Environment. The author has contributed to research in topics: Micronucleus test & Bone marrow. The author has an hindex of 11, co-authored 12 publications receiving 1594 citations.
Papers
More filters
Journal ArticleDOI
The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the U.S. Environmental Protection Agency Gene-Tox Program
TL;DR: The protocol recommended for the micronucleus assay in mammalian bone marrow has been revised and simplified and the minimum number of cells to be scored per treatment group has been increased to 20,000 to increase the ability of the assay to detect a doubling of the control micron nucleus frequency.
Journal ArticleDOI
Guidelines for the conduct of micronucleus assays in mammalian bone marrow erythrocytes.
James T. MacGregor,John A. Heddle,Mark Hite,Barry H. Margolin,Clacs Ramel,Michael F. Salamone,Raymond R. Tice,Dieter Wild +7 more
Journal ArticleDOI
Tradescantia micronucleus bioassay.
Te-Hsiu Ma,G.L Cabrera,R. Chen,B.S. Gill,Shahbeg S. Sandhu,A.L. Vandenberg,Michael F. Salamone +6 more
TL;DR: The data from this study suggest that under normal conditions, the Trad-MCNBioassay is an efficient and reliable short-term bioassay for clastogens, suitable for the rapid screening of chemicals, and also is specially qualified for in situ monitoring of ambient pollutants.
Journal ArticleDOI
Towards an improved micronucleus test: studies on 3 model agents, mitomycin C, cyclophosphamide and dimethylbenzanthracene.
TL;DR: It is concluded that multiple times are more valuable than multiple doses in detecting chromosomal breakage in vivo, and that any treatment within ∼10 h of sampling is ineffective.
Journal ArticleDOI
Tradescantia stamen hair mutation bioassay.
Te-Hsiu Ma,G.L Cabrera,A. Cebulska-Wasilewska,R. Chen,F. Loarca,A.L. Vandenberg,Michael F. Salamone +6 more
TL;DR: The results from the current study substantiate the Trad-SH assay as a reliable system for screening chemicals for their potential mutagenic effects and could be an effective in situ monitor of gaseous, liquid, and radioactive pollutants as well.