M
Michael L. Nielsen
Researcher at University of Copenhagen
Publications - 134
Citations - 15189
Michael L. Nielsen is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Proteome & Mass spectrometry. The author has an hindex of 48, co-authored 123 publications receiving 13104 citations. Previous affiliations of Michael L. Nielsen include University of Copenhagen Faculty of Health Sciences & University of Southern Denmark.
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Waves of sumoylation support transcription dynamics during adipocyte differentiation
Xu Zhao,Xu Zhao,Ivo A. Hendriks,Stéphanie Le Gras,Tao Ye,P Aurélie Nguéa,Guro Flor Lien,Lucia Ramos-Alonso,Lucia Ramos-Alonso,Arne Klungland,Bernard Jost,Jorrit M. Enserink,Michael L. Nielsen,Pierre Chymkowitch,Pierre Chymkowitch +14 more
TL;DR: In this paper, the sumoylation pathway has a dual function in differentiation; it supports the initial downregulation of pre-adipocyte-specific genes, while it promotes the establishment of the mature adipocyte transcriptional program.
Posted ContentDOI
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells
Samudyata,Paulo P. Amaral,Pär G. Engström,Samuel Robson,Michael L. Nielsen,Tony Kouzarides,Gonçalo Castelo-Branco +6 more
TL;DR: The results show that Sox 2 extensively interact with RBPs, and suggest that Sox2 and 7SK co-exist in a ribonucleoprotein complex whose function is not to regulate chromatin recruitment, but might rather regulate other processes in the nucleoplasm.
Journal ArticleDOI
Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington’s disease
Meeli Mullari,Nicolas Fossat,Niels H. Skotte,Andrea Asenjo-Martinez,David T. Humphreys,Jens Bukh,Agnete Kirkeby,Troels K. H. Scheel,Michael L. Nielsen +8 more