M
Michael L. Perdue
Researcher at Agricultural Research Service
Publications - 52
Citations - 7296
Michael L. Perdue is an academic researcher from Agricultural Research Service. The author has contributed to research in topics: Influenza A virus subtype H5N1 & Virus. The author has an hindex of 33, co-authored 52 publications receiving 7043 citations. Previous affiliations of Michael L. Perdue include United States Department of Agriculture & Centers for Disease Control and Prevention.
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Journal ArticleDOI
Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes
Christopher F. Basler,Ann H. Reid,Jody K. Dybing,Thomas A. Janczewski,Thomas G. Fanning,Hongyong Zheng,Mirella Salvatore,Michael L. Perdue,David E. Swayne,Adolfo García-Sastre,Peter Palese,Jeffery K. Taubenberger +11 more
TL;DR: The sequence of the A/Brevig Mission/1/18 (H1N1) virus nonstructural (NS) segment encoding two proteins, NS1 and nuclear export protein is reported, suggesting that interaction of the NS1 protein with host-cell factors plays a significant role in viral pathogenesis.
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Prevalence of Salmonellae, Listeria monocytogenes, and fecal coliforms in bulk tank milk on US dairies.
TL;DR: Although the prevalence of L. monocytogenes and Salmonella was low, these pathogens represent a potential risk to consumers of raw milk and raw milk products.
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Virulence-associated sequence duplication at the hemagglutinin cleavage site of avian influenza viruses
TL;DR: The complete HA nucleotide sequence of the isolate and phylogenetic relationship suggest that it was derived in direct succession from a non-pathogenic strain isolated about 1 month earlier, providing compelling support for a proposed model explaining the mechanism of spontaneous, virulence-related insertions in type A influenza viruses.
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Development of Real-Time RT-PCR for the Detection of Avian Influenza Virus
Erica Spackman,Dennis A. Senne,L. L. Bulaga,T. J. Myers,Michael L. Perdue,L. Garber,Kenton L. Lohman,Luke T. Daum,David L. Suarez +8 more
TL;DR: It is demonstrated that the AIV and H7 RRT-PCR assays are good tools for the rapid screening of flocks and LBMs.
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Baculovirus-derived hemagglutinin vaccines protect against lethal influenza infections by avian H5 and H7 subtypes.
John M. Crawford,Bethanie E. Wilkinson,Andrei Vosnesensky,Gale Smith,Maricarmen García,Henry D. Stone,Michael L. Perdue +6 more
TL;DR: When challenged with highly pathogenic strains of the corresponding AI subtypes, the vaccinated birds were completely protected against lethal infection and in some cases exhibited reduced or no cloacal shedding at 3 days postinfection.