M
Michael Pawlita
Researcher at German Cancer Research Center
Publications - 473
Citations - 30008
Michael Pawlita is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Cancer & Population. The author has an hindex of 78, co-authored 465 publications receiving 27107 citations. Previous affiliations of Michael Pawlita include Dartmouth College & Heidelberg University.
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Journal ArticleDOI
Case-control study of human papillomavirus and oropharyngeal cancer.
Aimée R. Kreimer,Raphael P. Viscidi,Michael Pawlita,Carole Fakhry,Wayne M. Koch,William H. Westra,Maura L. Gillison +6 more
TL;DR: Oropharyngeal cancer was significantly associated with oral HPV type 16 (HPV-16) infection, and the degree of association increased with the number of vaginal-sex and oral-sex partners, among subjects with or without the established risk factors of tobacco and alcohol use.
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Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor.
Frank C. Kischkel,Stefan Hellbardt,Iris Behrmann,Matthias Germer,Michael Pawlita,Peter H. Krammer,Marcus E. Peter +6 more
TL;DR: The data suggest that in vivo CAP1–4 are the APO‐1 apoptosis‐transducing molecules.
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Human papillomavirus and oral cancer: the International Agency for Research on Cancer multicenter study.
Rolando Herrero,Xavier Castellsagué,Michael Pawlita,Jolanta Lissowska,Frank Kee,Prabda Balaram,Thangarajan Rajkumar,Sridhar H,Barbara Rose,Javier Pintos,Leticia Fernandez,A.M. Idris,María José Sánchez,Adoración Nieto,Renato Talamini,Alessandra Tavani,F. Xavier Bosch,Ulrich Reidel,Peter J.F. Snijders,Chris J.L.M. Meijer,Raphael P. Viscidi,Nubia Muñoz,Silvia Franceschi +22 more
TL;DR: HPV appears to play an etiologic role in many cancers of the oropharynx and possibly a small subgroup of cancers of The most common HPV type in genital cancers (HPV16) was also the most common in these tumors.
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Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen.
A. Oehm,Iris Behrmann,Werner Falk,Michael Pawlita,Gerhard Maier,C. Klas,Min Li-Weber,S. Richards,Jens Dhein,B. C. Trauth +9 more
TL;DR: The APO-1 antigen was expressed upon transfection of APo-1 cDNA into BL60-P7 Burkitt's lymphoma cells and conferred sensitivity towards anti-APO- 1-induced apoptosis to the transfectants.
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A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen.
Serge J. Smeets,Albertus T. Hesselink,Ernst-Jan M. Speel,Annick Haesevoets,Peter J.F. Snijders,Michael Pawlita,Chris J.L.M. Meijer,Boudewijn J.M. Braakhuis,C. René Leemans,Ruud H. Brakenhoff +9 more
TL;DR: It is shown that clinically meaningful viral HPV infections can be more reliably measured in FFPE H NSCC samples in a standard and high throughput manner, paving the way for prognostic and experimental vaccination studies, regarding not only HNSCC, but possibly also cancer types with HPV involvement in subgroups such as penile and anal cancer.