M
Michael S. Haney
Researcher at Stanford University
Publications - 27
Citations - 2770
Michael S. Haney is an academic researcher from Stanford University. The author has contributed to research in topics: CRISPR & Genome. The author has an hindex of 13, co-authored 24 publications receiving 1436 citations.
Papers
More filters
Journal ArticleDOI
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse
Nicole Almanzar,Jane Antony,Ankit S. Baghel,Isaac Bakerman,Ishita Bansal,Ben A. Barres,Philip A. Beachy,Daniela Berdnik,Biter Bilen,Douglas Brownfield,Corey Cain,Charles Chan,Michelle B. Chen,Michael F. Clarke,Stephanie D. Conley,Spyros Darmanis,Aaron Demers,Kubilay Demir,Antoine de Morrée,Tessa Divita,Haley du Bois,Hamid Ebadi,F. Hernan Espinoza,Matt Fish,Qiang Gan,Benson M. George,Astrid Gillich,Rafael Gòmez-Sjöberg,Foad Green,Geraldine Genetiano,Xueying Gu,Gunsagar S. Gulati,Oliver Hahn,Michael S. Haney,Yan Hang,Lincoln Harris,Mu He,Shayan Hosseinzadeh,Albin Huang,Kerwyn Casey Huang,Tal Iram,Taichi Isobe,Feather Ives,Robert C. Jones,Kevin S. Kao,Jim Karkanias,Guruswamy Karnam,Andreas Keller,Aaron M. Kershner,Nathalie Khoury,Seung K. Kim,Bernhard M. Kiss,William Kong,Mark A. Krasnow,Maya E. Kumar,Christin S. Kuo,Jonathan K. Lam,Davis P. Lee,Song E. Lee,Benoit Lehallier,Olivia Leventhal,Guang Li,Qingyun Li,Ling Liu,Annie Lo,Wan Jin Lu,Maria F. Lugo-Fagundo,Anoop Manjunath,Andrew May,Ashley Maynard,Aaron McGeever,Marina McKay,M. Windy McNerney,Bryan D. Merrill,Ross J. Metzger,Marco Mignardi,Dullei Min,Ahmad N. Nabhan,Norma Neff,Katharine M. Ng,Patricia K. Nguyen,Joseph Noh,Roel Nusse,Róbert Pálovics,Rasika Patkar,Weng Chuan Peng,Lolita Penland,Angela Oliveira Pisco,Katherine S. Pollard,Robert Puccinelli,Zhen Qi,Stephen R. Quake,Thomas A. Rando,Eric J. Rulifson,Nicholas Schaum,Joe M. Segal,Shaheen S. Sikandar,Rahul Sinha,Rene V. Sit,Justin L. Sonnenburg,Daniel Staehli,Krzysztof Szade,Michelle Tan,Weilun Tan,Cristina M. Tato,Krissie Tellez,Laughing Bear Torrez Dulgeroff,Kyle J. Travaglini,Carolina Tropini,Margaret Tsui,Lucas M. Waldburger,Bruce Wang,Linda J. van Weele,Kenneth I. Weinberg,Irving L. Weissman,Michael N. Wosczyna,Sean M. Wu,Tony Wyss-Coray,Jinyi Xiang,Soso Xue,Kevin A. Yamauchi,Andrew C. Yang,Lakshmi P. Yerra,Justin Youngyunpipatkul,Brian Yu,Fabio Zanini,Macy E. Zardeneta,Alexander Zee,Chunyu Zhao,Fan Zhang,Hui Zhang,Martin J. Zhang,Lu Zhou,James Zou +133 more
Journal ArticleDOI
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
Julia Marschallinger,Julia Marschallinger,Tal Iram,Macy E. Zardeneta,Song E. Lee,Benoit Lehallier,Michael S. Haney,John V. Pluvinage,Vidhu Mathur,Oliver Hahn,David W. Morgens,Justin Kim,Julia Tevini,Thomas K. Felder,Heimo Wolinski,Carolyn R. Bertozzi,Michael C. Bassik,Michael C. Bassik,Ludwig Aigner,Tony Wyss-Coray +19 more
TL;DR: A striking buildup of lipid droplets in microglia with aging in mouse and human brains is reported, and it is proposed that LDAM contribute to age-related and genetic forms of neurodegeneration.
Journal ArticleDOI
Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells
Alexej Abyzov,Jessica Mariani,Dean Palejev,Ying Zhang,Michael S. Haney,Livia Tomasini,Anthony F. Ferrandino,Lior A. Rosenberg Belmaker,Anna Szekely,Michael Wilson,Arif Kocabas,Nathaniel E. Calixto,Elena L. Grigorenko,Anita Huttner,Katarzyna Chawarska,Sherman M. Weissman,Alexander E. Urban,Alexander E. Urban,Mark Gerstein,Flora M. Vaccarino +19 more
TL;DR: A whole-genome and transcriptome analysis of 20 human iPSC lines derived from the primary skin fibroblasts finds that approximately 30% of the fibroblast cells have somatic CNVs in their genomes, suggesting widespread somatic mosaicism in the human body.
Journal ArticleDOI
Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens
David W. Morgens,Michael Wainberg,Evan A. Boyle,Oana Ursu,Carlos L. Araya,C. Kimberly Tsui,Michael S. Haney,Gaelen T. Hess,Kyuho Han,Edwin E. Jeng,Amy Li,Michael Snyder,William J. Greenleaf,Anshul Kundaje,Michael C. Bassik +14 more
TL;DR: A CRISPR-Cas9 library with 10 variable-length guides per gene and thousands of negative controls targeting non-functional, non-genic regions (termed safe-targeting guides) has excellent performance in identifying genes affecting growth and sensitivity to the ricin toxin.
Posted ContentDOI
Lipid droplet accumulating microglia represent a dysfunctional and pro-inflammatory state in the aging brain
Julia Marschallinger,Julia Marschallinger,Tal Iram,Macy E. Zardeneta,Song E. Lee,Benoit Lehallier,Michael S. Haney,John V. Pluvinage,Vidhu Mathur,Oliver Hahn,David W. Morgens,Justin Kim,Julia Tevini,Thomas K. Felder,Heimo Wolinski,Carolyn R. Bertozzi,Michael C. Bassik,Michael C. Bassik,Ludwig Aigner,Tony Wyss-Coray +19 more
TL;DR: A striking buildup of lipid droplets in microglia with aging in mouse and human brains is reported and it is proposed that LAM contribute to age-related and genetic forms of neurodegeneration.